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Spyre Therapeutics

68 hedge funds and large institutions have $158M invested in Spyre Therapeutics in 2019 Q4 according to their latest regulatory filings, with 9 funds opening new positions, 20 increasing their positions, 16 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

25% more repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 16

2% more capital invested

Capital invested by funds: $154M → $158M (+$3.44M)

0.07% more ownership

Funds ownership: 2.78%2.85% (+0.07%)

4% less funds holding

Funds holding: 7168 (-3)

25% less first-time investments, than exits

New positions opened: 9 | Existing positions closed: 12

Holders
68
Holders Change
-3
Holders Change %
-4.23%
% of All Funds
1.34%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.08%
New
9
Increased
20
Reduced
16
Closed
12
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Deutsche Bank
26
Deutsche Bank
Germany
$486K +$445K +2,269 +805%
Charles Schwab
27
Charles Schwab
California
$456K
Wells Fargo
28
Wells Fargo
California
$425K -$589 -3 -0.1%
UBS Group
29
UBS Group
Switzerland
$420K -$28.9K -147 -6%
SCA
30
Snowden Capital Advisors
New York
$392K +$403K +2,051 New
Two Sigma Investments
31
Two Sigma Investments
New York
$379K +$390K +1,985 New
JP Morgan Chase
32
JP Morgan Chase
New York
$371K -$50.2K -256 -12%
Squarepoint
33
Squarepoint
New York
$368K -$178K -905 -32%
Man Group
34
Man Group
United Kingdom
$315K
California Public Employees Retirement System
35
California Public Employees Retirement System
California
$313K +$322K +1,640 New
California State Teachers Retirement System (CalSTRS)
36
California State Teachers Retirement System (CalSTRS)
California
$308K
State of Wisconsin Investment Board
37
State of Wisconsin Investment Board
Wisconsin
$303K +$158K +805 +103%
RhumbLine Advisers
38
RhumbLine Advisers
Massachusetts
$286K +$1.37K +7 +0.5%
Morgan Stanley
39
Morgan Stanley
New York
$276K +$220K +1,120 +345%
Prudential Financial
40
Prudential Financial
New Jersey
$258K -$1.57K -8 -0.6%
Two Sigma Advisers
41
Two Sigma Advisers
New York
$251K +$133K +680 +107%
FSA
42
Franklin Street Advisors
North Carolina
$229K
William Blair & Company
43
William Blair & Company
Illinois
$208K
Barclays
44
Barclays
United Kingdom
$202K +$101K +514 +94%
Bank of America
45
Bank of America
North Carolina
$191K -$22.2K -113 -10%
LF
46
Lee Financial
Texas
$171K
New York State Common Retirement Fund
47
New York State Common Retirement Fund
New York
$144K -$61.2K -312 -29%
Manulife (Manufacturers Life Insurance)
48
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$133K -$17.5K -89 -11%
AIG
49
American International Group
New York
$125K -$1.18K -6 -0.9%
Citadel Advisors
50
Citadel Advisors
Florida
$111K +$114K +580 New

SYRE Hedge Fund Activity: Q4 2019 in Review

68 of the 5,076 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q4 2019, worth a combined $158M — up 2.2% from $154M a quarter earlier.

Sellers outnumbered buyers: 12 funds closed out of SYRE and 9 opened new positions — a net loss of 3 holders — while 16 trimmed existing stakes and 20 added.

The largest buyer was P.A.W. Capital, opening a new position worth an estimated $785K. The largest seller was Deerfield Management, exiting entirely with an estimated $3.85M sold.

  • 68 institutional investors held Spyre Therapeutics (SYRE) as of Q4 2019, down from 71 in Q3 2019.
  • Funds reported $158M of Spyre Therapeutics stock for Q4 2019, up 2.2% quarter-over-quarter.
  • 9 funds opened new Spyre Therapeutics positions in Q4 2019 and 12 closed out, a net change of -3 holders.
  • The largest Spyre Therapeutics buyer in Q4 2019 was P.A.W. Capital, an estimated $785K added.
  • The largest Spyre Therapeutics seller in Q4 2019 was Deerfield Management, an estimated $3.85M sold.

Based on aggregated 13F filings for Q4 2019.