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Spyre Therapeutics
SYRE

Overview Fund Activity

77 hedge funds and large institutions have $137M invested in Spyre Therapeutics in 2019 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 35 increasing their positions, 9 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
77
Holders Change
+6
Holders Change %
+8.45%
% of All Funds
1.68%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.07%
New
16
Increased
35
Reduced
9
Closed
8
Calls
–
Puts
$1K
Net Calls
-$1K
Net Calls Change
-$1K

Top Buyers

1
BlackRock
BlackRock
New York
+$2.5M
2
Marshall Wace
Marshall Wace
United Kingdom
+$1.94M
3
NCM
Nantahala Capital Management
Connecticut
+$1.37M
4
AG
Artal Group
Luxembourg
+$1.16M
5
State Street
State Street
Massachusetts
+$954K

Top Sellers

1
Jennison Associates
Jennison Associates
New York
-$6.25M
2
SFM
Sphera Funds Management
Israel
-$5.4M
3
CH
CVI Holdings
Delaware
-$2.19M
4
Citadel Advisors
Citadel Advisors
Florida
-$611K
5
MWNA
Marshall Wace North America
New York
-$179K
Name Holding Trade Value Shares
Change 		Shares
Change %
Bank of New York Mellon
26
Bank of New York Mellon
New York
$654K +$233K +1,361 +55%
Man Group
27
Man Group
United Kingdom
$628K +$11K +64 +2%
Millennium Management
28
Millennium Management
New York
$520K +$420K +2,454 +422%
Wells Fargo
29
Wells Fargo
California
$419K +$142K +830 +51%
Charles Schwab
30
Charles Schwab
California
$409K +$104K +605 +34%
OAM
31
Oxford Asset Management
United Kingdom
$378K +$264K +1,540 +232%
Squarepoint
32
Squarepoint
New York
$362K +$96.7K +565 +36%
D.E. Shaw & Co
33
D.E. Shaw & Co
New York
$345K +$216K +1,259 +167%
JPMorgan Chase & Co
34
JPMorgan Chase & Co
New York
$343K +$300K +1,871 +701%
Two Sigma Investments
35
Two Sigma Investments
New York
$339K +$339K +1,978 New
Morgan Stanley
36
Morgan Stanley
New York
$337K +$277K +1,621 +461%
DAM
37
Deltec Asset Management
New York
$328K +$65.8K +384 +25%
Jacobs Levy Equity Management
38
Jacobs Levy Equity Management
New Jersey
$328K +$328K +1,914 New
UBS Group
39
UBS Group
Switzerland
$293K +$4.46K +26 +2%
California State Teachers Retirement System (CalSTRS)
40
California State Teachers Retirement System (CalSTRS)
California
$276K +$73.3K +428 +36%
RhumbLine Advisers
41
RhumbLine Advisers
Massachusetts
$235K +$70.1K +410 +42%
FSA
42
Franklin Street Advisors
North Carolina
$206K – – –
Citadel Advisors
43
Citadel Advisors
Florida
$203K -$611K -3,579 -75%
William Blair & Company
44
William Blair & Company
Illinois
$186K – – –
New York State Common Retirement Fund
45
New York State Common Retirement Fund
New York
$184K +$125K +728 +212%
Bank of America
46
Bank of America
North Carolina
$182K +$87.9K +512 +93%
Prudential Financial
47
Prudential Financial
New Jersey
$162K +$162K +944 New
LF
48
Lee Financial
Texas
$153K – – –
State of Wisconsin Investment Board
49
State of Wisconsin Investment Board
Wisconsin
$151K +$3.42K +20 +2%
AG
50
Algert Global
California
$151K +$25.3K +148 +20%
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