SYRE icon

Spyre Therapeutics
SYRE

Overview Fund Activity

84 hedge funds and large institutions have $328M invested in Spyre Therapeutics in 2021 Q1 according to their latest regulatory filings, with 3 funds opening new positions, 23 increasing their positions, 32 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
84
Holders Change
-8
Holders Change %
-8.7%
% of All Funds
1.48%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
3
Increased
23
Reduced
32
Closed
11
Calls
$340K
Puts
$119K
Net Calls
+$221K
Net Calls Change
+$770K

Top Buyers

1
Goldman Sachs
Goldman Sachs
New York
+$5.56M
2
SCM
Suvretta Capital Management
New York
+$4.82M
3
GPP
Great Point Partners
Connecticut
+$3.98M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$1.76M
5
SCM
Sio Capital Management
New York
+$1.68M

Top Sellers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$11.3M
2
NCM
Nantahala Capital Management
Connecticut
-$2.08M
3
DCM
Driehaus Capital Management
Illinois
-$1.91M
4
Millennium Management
Millennium Management
New York
-$697K
5
Russell Investments Group
Russell Investments Group
United Kingdom
-$447K
Name Holding Trade Value Shares
Change 		Shares
Change %
TRCT
76
Tower Research Capital (TRC)
New York
$21K -$46.4K -234 -69%
OSAM
77
O'Shaughnessy Asset Management
Connecticut
$13K – – –
FIA
78
FNY Investment Advisers
New York
$11K +$11K +60 New
QCG
79
Quadrant Capital Group
Ohio
$9K – – –
PCM
80
Penserra Capital Management
California
$8K – – –
Group One Trading
81
Group One Trading
Illinois
$2K – – –
Daiwa Securities Group
82
Daiwa Securities Group
Japan
$1K – – –
EI
83
Ellevest Inc
New York
$1K +$400 +2 +67%
AIG
84
American International Group
New York
$208 – +2 +0.2%
GCP
85
GSA Capital Partners
United Kingdom
– -$384K -1,953 Closed
Citadel Advisors
86
Citadel Advisors
Florida
– -$265K -1,349 Closed
LF
87
Lee Financial
Texas
– -$176K -896 Closed
TI
88
Trexquant Investment
Connecticut
– -$158K -805 Closed
VF
89
Virtu Financial
New York
– -$97K -494 Closed
CS
90
Credit Suisse
Switzerland
– -$91K -464 Closed
Susquehanna International Group
91
Susquehanna International Group
Pennsylvania
– -$84K -426 Closed
Principal Financial Group
92
Principal Financial Group
Iowa
– -$79K -401 Closed
PWPS
93
Pinnacle Wealth Planning Services
Ohio
– -$1K -6 Closed
1 2 3
4