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Spyre Therapeutics

94 hedge funds and large institutions have $275M invested in Spyre Therapeutics in 2020 Q3 according to their latest regulatory filings, with 17 funds opening new positions, 23 increasing their positions, 31 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

70% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 10

8% more funds holding

Funds holding: 8794 (+7)

0.07% more ownership

Funds ownership: 3.41%3.48% (+0.07%)

22% less capital invested

Capital invested by funds: $352M → $275M (-$76.7M)

26% less repeat investments, than reductions

Existing positions increased: 23 | Existing positions reduced: 31

33% less funds holding in top 10

Funds holding in top 10: 32 (-1)

Holders
94
Holders Change
+7
Holders Change %
+8.05%
% of All Funds
1.9%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.04%
New
17
Increased
23
Reduced
31
Closed
10
Calls
$1K
Puts
Net Calls
+$1K
Net Calls Change
+$1K
Name Holding Trade Value Shares
Change
Change in
Stake
UOTTAIMCU
26
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$1.98M
Jacobs Levy Equity Management
27
Jacobs Levy Equity Management
New Jersey
$1.71M +$1.79M +9,659 New
A
28
Abingworth
United Kingdom
$1.7M
SCM
29
Sio Capital Management
New York
$1.5M
RWM
30
Ritholtz Wealth Management
New York
$1.24M
N
31
Nuveen
North Carolina
$1.18M -$312K -1,684 -20%
Russell Investments Group
32
Russell Investments Group
United Kingdom
$1.17M +$741K +4,007 +153%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$1.07M +$79K +427 +8%
Two Sigma Investments
34
Two Sigma Investments
New York
$998K +$432K +2,334 +71%
Assenagon Asset Management
35
Assenagon Asset Management
Luxembourg
$860K -$1.56M -8,455 -64%
AG
36
Algert Global
California
$766K +$800K +4,322 New
Charles Schwab
37
Charles Schwab
California
$750K -$23.7K -128 -3%
D.E. Shaw & Co
38
D.E. Shaw & Co
New York
$669K +$9.62K +52 +1%
California Public Employees Retirement System
39
California Public Employees Retirement System
California
$618K -$43.7K -236 -6%
FSA
40
Franklin Street Advisors
North Carolina
$521K +$174K +940 +47%
State of Wisconsin Investment Board
41
State of Wisconsin Investment Board
Wisconsin
$481K +$502K +2,712 New
Deutsche Bank
42
Deutsche Bank
Germany
$465K +$15K +81 +3%
California State Teachers Retirement System (CalSTRS)
43
California State Teachers Retirement System (CalSTRS)
California
$449K
SCA
44
Snowden Capital Advisors
New York
$407K +$43.7K +236 +11%
Two Sigma Advisers
45
Two Sigma Advisers
New York
$406K +$107K +580 +34%
GCP
46
GSA Capital Partners
United Kingdom
$389K +$406K +2,196 New
William Blair & Company
47
William Blair & Company
Illinois
$370K
Bank of America
48
Bank of America
North Carolina
$351K +$223K +1,207 +156%
Citadel Advisors
49
Citadel Advisors
Florida
$337K +$143K +775 +69%
RhumbLine Advisers
50
RhumbLine Advisers
Massachusetts
$321K -$45.9K -248 -12%

SYRE Hedge Fund Activity: Q3 2020 in Review

94 of the 4,957 institutional investors tracked by Wall St. Rank reported a position in Spyre Therapeutics (SYRE) for Q3 2020, worth a combined $275M — down 22% from $352M a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new SYRE positions and 10 closed out — a net gain of 7 holders — while 23 added to existing stakes and 31 trimmed.

The largest buyer was Pictet Asset Management (UK), opening a new position worth an estimated $8.41M. The largest seller was Deerfield Management, exiting entirely with an estimated $7.63M sold.

  • 94 institutional investors held Spyre Therapeutics (SYRE) as of Q3 2020, up from 87 in Q2 2020.
  • Funds reported $275M of Spyre Therapeutics stock for Q3 2020, down 22% quarter-over-quarter.
  • 17 funds opened new Spyre Therapeutics positions in Q3 2020 and 10 closed out, a net change of +7 holders.
  • The largest Spyre Therapeutics buyer in Q3 2020 was Pictet Asset Management (UK), an estimated $8.41M added.
  • The largest Spyre Therapeutics seller in Q3 2020 was Deerfield Management, an estimated $7.63M sold.

Based on aggregated 13F filings for Q3 2020.