SYRE icon

Spyre Therapeutics
SYRE

Overview Fund Activity

87 hedge funds and large institutions have $352M invested in Spyre Therapeutics in 2020 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 43 increasing their positions, 13 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
87
Holders Change
+17
Holders Change %
+24.29%
% of All Funds
1.79%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.06%
New
25
Increased
43
Reduced
13
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$25M
2
BBA
Baker Bros. Advisors
New York
+$24.7M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$13.2M
4
BlackRock
BlackRock
New York
+$12.1M
5
O
OrbiMed
New York
+$10.6M

Top Sellers

1
SCM
Soleus Capital Management
Connecticut
-$1.54M
2
BCM
Bridgeway Capital Management
Texas
-$534K
3
RWM
Ritholtz Wealth Management
New York
-$462K
4
Renaissance Technologies
Renaissance Technologies
New York
-$422K
5
UOTTAIMCU
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
-$398K
Name Holding Trade Value Shares
Change 		Shares
Change %
A
26
Abingworth
United Kingdom
$2.22M – – –
SCM
27
Sio Capital Management
New York
$1.95M +$1.95M +8,444 New
Nuveen Asset Management
28
Nuveen Asset Management
Illinois
$1.93M +$1.11M +4,792 +135%
Millennium Management
29
Millennium Management
New York
$1.7M +$1.57M +6,781 +1,217%
RWM
30
Ritholtz Wealth Management
New York
$1.62M -$462K -2,000 -22%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$1.3M +$422K +1,825 +48%
SCM
32
Suvretta Capital Management
New York
$1.09M +$1.09M +4,717 New
Charles Schwab
33
Charles Schwab
California
$1.01M +$447K +1,932 +80%
California Public Employees Retirement System
34
California Public Employees Retirement System
California
$860K +$481K +2,080 +127%
D.E. Shaw & Co
35
D.E. Shaw & Co
New York
$860K +$608K +2,628 +241%
Two Sigma Investments
36
Two Sigma Investments
New York
$762K +$435K +1,880 +133%
Russell Investments Group
37
Russell Investments Group
United Kingdom
$603K +$26.3K +114 +5%
Deutsche Bank
38
Deutsche Bank
Germany
$588K +$116K +501 +25%
California State Teachers Retirement System (CalSTRS)
39
California State Teachers Retirement System (CalSTRS)
California
$586K +$209K +903 +55%
Invesco
40
Invesco
Georgia
$580K +$580K +2,507 New
William Blair & Company
41
William Blair & Company
Illinois
$483K +$231K +1,000 +92%
SCA
42
Snowden Capital Advisors
New York
$477K – – –
RhumbLine Advisers
43
RhumbLine Advisers
Massachusetts
$477K +$126K +543 +36%
FSA
44
Franklin Street Advisors
North Carolina
$463K +$139K +600 +43%
UBS Group
45
UBS Group
Switzerland
$403K -$4.16K -18 -1%
Two Sigma Advisers
46
Two Sigma Advisers
New York
$395K +$88.8K +384 +29%
Squarepoint
47
Squarepoint
New York
$359K +$139K +601 +63%
New York State Common Retirement Fund
48
New York State Common Retirement Fund
New York
$355K +$180K +780 +103%
Qube Research & Technologies (QRT)
49
Qube Research & Technologies (QRT)
United Kingdom
$334K +$334K +1,444 New
Wells Fargo
50
Wells Fargo
California
$313K -$320K -1,385 -51%
1
2
3 4