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Spyre Therapeutics
SYRE

Overview Fund Activity

77 hedge funds and large institutions have $137M invested in Spyre Therapeutics in 2019 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 35 increasing their positions, 9 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
77
Holders Change
+6
Holders Change %
+8.45%
% of All Funds
1.68%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.07%
New
16
Increased
35
Reduced
9
Closed
8
Calls
–
Puts
$1K
Net Calls
-$1K
Net Calls Change
-$1K

Top Buyers

1
BlackRock
BlackRock
New York
+$2.5M
2
Marshall Wace
Marshall Wace
United Kingdom
+$1.94M
3
NCM
Nantahala Capital Management
Connecticut
+$1.37M
4
AG
Artal Group
Luxembourg
+$1.16M
5
State Street
State Street
Massachusetts
+$954K

Top Sellers

1
Jennison Associates
Jennison Associates
New York
-$6.25M
2
SFM
Sphera Funds Management
Israel
-$5.4M
3
CH
CVI Holdings
Delaware
-$2.19M
4
Citadel Advisors
Citadel Advisors
Florida
-$611K
5
MWNA
Marshall Wace North America
New York
-$179K
Name Holding Trade Value Shares
Change 		Shares
Change %
AQR Capital Management
51
AQR Capital Management
Connecticut
$143K -$50.2K -294 -26%
ARTA
52
A.R.T. Advisors
New York
$143K +$143K +833 New
Manulife (Manufacturers Life Insurance)
53
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$134K +$134K +781 New
Barclays
54
Barclays
United Kingdom
$118K +$32.4K +189 +38%
Deutsche Bank
55
Deutsche Bank
Germany
$115K -$40K -236 -26%
AIG
56
American International Group
New York
$114K +$30.5K +178 +37%
LI
57
Leap Investments
Illinois
$114K +$114K +664 New
Two Sigma Advisers
58
Two Sigma Advisers
New York
$95K +$95K +552 New
SAM
59
Sectoral Asset Management
Quebec, Canada
$89K – – –
Susquehanna International Group
60
Susquehanna International Group
Pennsylvania
$83K +$83K +483 New
ProShare Advisors
61
ProShare Advisors
Maryland
$72K -$6.55K -38 -8%
Commonwealth Equity Services
62
Commonwealth Equity Services
Massachusetts
$68K +$68K +400 New
Citigroup
63
Citigroup
New York
$51K +$12K +70 +31%
Bank of Montreal
64
Bank of Montreal
Ontario, Canada
$47K +$25.2K +145 +116%
SO
65
STRS Ohio
Ohio
$32K – – –
Legal & General Group
66
Legal & General Group
United Kingdom
$30K +$8.07K +50 +37%
Ohio Public Employees Retirement System (OPERS)
67
Ohio Public Employees Retirement System (OPERS)
Ohio
$27K +$27K +156 New
BNP Paribas Financial Markets
68
BNP Paribas Financial Markets
France
$14.9K -$12.7K -74 -46%
PAM
69
Panagora Asset Management
Massachusetts
$14K +$14K +84 New
Simplex Trading
70
Simplex Trading
Illinois
$14K +$14K +85 New
AIP
71
Ameritas Investment Partners
Nebraska
$9K – – –
LTFS
72
Ladenburg Thalmann Financial Services
Florida
$5K – – –
Russell Investments Group
73
Russell Investments Group
United Kingdom
$3K +$3K +16 New
MAM
74
Meeder Asset Management
Ohio
$2K -$41.5K -270 -95%
Royal Bank of Canada
75
Royal Bank of Canada
Ontario, Canada
$2K +$857 +6 +75%
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