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Spyre Therapeutics
SYRE

Overview Fund Activity

60 hedge funds and large institutions have $123M invested in Spyre Therapeutics in 2018 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 18 increasing their positions, 16 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
60
Holders Change
+1
Holders Change %
+1.69%
% of All Funds
1.34%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.04%
New
10
Increased
18
Reduced
16
Closed
9
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$4.07M
2
BBA
Baker Bros. Advisors
New York
+$2.44M
3
RWM
Ritholtz Wealth Management
New York
+$2.18M
4
BlackRock
BlackRock
New York
+$2.06M
5
Dimensional Fund Advisors
Dimensional Fund Advisors
Texas
+$898K

Top Sellers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$2.54M
2
Jennison Associates
Jennison Associates
New York
-$1.35M
3
Man Group
Man Group
United Kingdom
-$1.31M
4
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$519K
5
SFM
Sphera Funds Management
Israel
-$398K
Name Holding Trade Value Shares
Change 		Shares
Change %
Bank of Montreal
51
Bank of Montreal
Ontario, Canada
$25K -$14.6K -77 -37%
Legal & General Group
52
Legal & General Group
United Kingdom
$18K – – –
TRCT
53
Tower Research Capital (TRC)
New York
$17K +$15.9K +87 +1,450%
DWA
54
Dorsey Wright & Associates
California
$12K +$2.03K +11 +20%
AIP
55
Ameritas Investment Partners
Nebraska
$10K – – –
LTFS
56
Ladenburg Thalmann Financial Services
Florida
$6K – – –
AG
57
Advisor Group
Arizona
$5K – – –
Federated Hermes
58
Federated Hermes
Pennsylvania
$4K -$6.4K -32 -62%
Royal Bank of Canada
59
Royal Bank of Canada
Ontario, Canada
$1K -$25.9K -207 -96%
IA
60
IFP Advisors
Florida
$1K +$1K +5 New
Point72 Asset Management
61
Point72 Asset Management
Connecticut
– -$2.54M -10,625 Closed
Acadian Asset Management
62
Acadian Asset Management
Massachusetts
– -$519K -2,169 Closed
OAM
63
Oxford Asset Management
United Kingdom
– -$338K -1,418 Closed
Two Sigma Investments
64
Two Sigma Investments
New York
– -$252K -1,055 Closed
Invesco
65
Invesco
Georgia
– -$252K -1,053 Closed
Barclays
66
Barclays
United Kingdom
– -$59K -245 Closed
PHK
67
Point72 Hong Kong
Hong Kong
– -$15K -61 Closed
MCM
68
Mainstay Capital Management
Michigan
– -$10K -40 Closed
BNP Paribas Financial Markets
69
BNP Paribas Financial Markets
France
– -$5.1K -21 Closed
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