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Spyre Therapeutics
SYRE

Overview Fund Activity

71 hedge funds and large institutions have $159M invested in Spyre Therapeutics in 2019 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 25 increasing their positions, 12 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
71
Holders Change
+11
Holders Change %
+18.33%
% of All Funds
1.54%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.09%
New
17
Increased
25
Reduced
12
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
DM
Deerfield Management
New York
+$4.03M
2
Goldman Sachs
Goldman Sachs
New York
+$3.11M
3
Marshall Wace
Marshall Wace
United Kingdom
+$3.03M
4
SFM
Sphera Funds Management
Israel
+$3.02M
5
ACM
Aisling Capital Management
New York
+$2.84M

Top Sellers

1
Jennison Associates
Jennison Associates
New York
-$4.63M
2
Man Group
Man Group
United Kingdom
-$276K
3
Squarepoint
Squarepoint
New York
-$167K
4
Morgan Stanley
Morgan Stanley
New York
-$147K
5
TI
Trexquant Investment
Connecticut
-$116K
Name Holding Trade Value Shares
Change 		Shares
Change %
Assenagon Asset Management
26
Assenagon Asset Management
Luxembourg
$757K +$757K +3,761 New
Man Group
27
Man Group
United Kingdom
$725K -$276K -1,372 -28%
Bank of New York Mellon
28
Bank of New York Mellon
New York
$495K +$96.8K +481 +24%
Charles Schwab
29
Charles Schwab
California
$359K +$27K +134 +8%
UBS Group
30
UBS Group
Switzerland
$339K -$4.23K -21 -1%
Wells Fargo
31
Wells Fargo
California
$326K +$11.3K +56 +4%
Squarepoint
32
Squarepoint
New York
$312K -$167K -828 -35%
DAM
33
Deltec Asset Management
New York
$308K – – –
FSA
34
Franklin Street Advisors
North Carolina
$242K +$80.7K +400 +50%
TA
35
Teachers Advisors
New York
$238K – – –
California State Teachers Retirement System (CalSTRS)
36
California State Teachers Retirement System (CalSTRS)
California
$238K +$30.4K +151 +15%
AQR Capital Management
37
AQR Capital Management
Connecticut
$228K – – –
William Blair & Company
38
William Blair & Company
Illinois
$219K – – –
RhumbLine Advisers
39
RhumbLine Advisers
Massachusetts
$194K +$20.5K +102 +12%
Deutsche Bank
40
Deutsche Bank
Germany
$183K +$29.2K +146 +19%
LF
41
Lee Financial
Texas
$180K – – –
MWNA
42
Marshall Wace North America
New York
$179K +$179K +892 New
State of Wisconsin Investment Board
43
State of Wisconsin Investment Board
Wisconsin
$174K +$39.5K +196 +29%
TCIM
44
TIAA CREF Investment Management
New York
$152K – – –
D.E. Shaw & Co
45
D.E. Shaw & Co
New York
$152K +$152K +756 New
AG
46
Algert Global
California
$148K -$59.1K -293 -29%
OAM
47
Oxford Asset Management
United Kingdom
$134K +$134K +665 New
Millennium Management
48
Millennium Management
New York
$117K -$51.2K -254 -30%
Bank of America
49
Bank of America
North Carolina
$111K -$28K -138 -20%
SAM
50
Sectoral Asset Management
Quebec, Canada
$104K – – –
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