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Spyre Therapeutics
SYRE

Overview Fund Activity

64 hedge funds and large institutions have $155M invested in Spyre Therapeutics in 2018 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 22 increasing their positions, 4 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
64
Holders Change
+26
Holders Change %
+68.42%
% of All Funds
1.47%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
32
Increased
22
Reduced
4
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
BlackRock
BlackRock
New York
+$8.44M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$6.78M
3
SFM
Sphera Funds Management
Israel
+$5.39M
4
Renaissance Technologies
Renaissance Technologies
New York
+$4.51M
5
Millennium Management
Millennium Management
New York
+$4.26M

Top Sellers

1
UOTTAIMCU
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
-$1.95M
2
DZ Bank
DZ Bank
Germany
-$649K
3
SIM
Spark Investment Management
New York
-$188K
4
ARTA
A.R.T. Advisors
New York
-$183K
5
PAM
Panagora Asset Management
Massachusetts
-$158K
Name Holding Trade Value Shares
Change 		Shares
Change %
Acadian Asset Management
26
Acadian Asset Management
Massachusetts
$773K +$447K +1,690 +137%
EI
27
EAM Investors
California
$600K – – –
Wells Fargo
28
Wells Fargo
California
$552K +$264K +997 +91%
Bank of New York Mellon
29
Bank of New York Mellon
New York
$438K +$438K +1,656 New
Morgan Stanley
30
Morgan Stanley
New York
$427K +$348K +1,315 +443%
Invesco
31
Invesco
Georgia
$382K +$382K +1,443 New
SLG
32
Stanley-Laman Group
Pennsylvania
$371K +$244K +923 +193%
Squarepoint
33
Squarepoint
New York
$350K +$238K +900 +212%
Charles Schwab
34
Charles Schwab
California
$321K +$321K +1,212 New
William Blair & Company
35
William Blair & Company
Illinois
$288K – – –
PA
36
Perceptive Advisors
New York
$272K +$272K +1,028 New
TCIM
37
TIAA CREF Investment Management
New York
$265K +$265K +1,000 New
California State Teachers Retirement System (CalSTRS)
38
California State Teachers Retirement System (CalSTRS)
California
$264K +$264K +998 New
EMG
39
Ellington Management Group
Connecticut
$262K +$262K +992 New
LF
40
Lee Financial
Texas
$237K – – –
TA
41
Teachers Advisors
New York
$226K +$226K +853 New
AQR Capital Management
42
AQR Capital Management
Connecticut
$211K +$211K +797 New
New York State Common Retirement Fund
43
New York State Common Retirement Fund
New York
$191K +$191K +724 New
Goldman Sachs
44
Goldman Sachs
New York
$181K +$55.4K +210 +44%
RhumbLine Advisers
45
RhumbLine Advisers
Massachusetts
$161K +$161K +609 New
Manulife (Manufacturers Life Insurance)
46
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$145K +$145K +550 New
Jacobs Levy Equity Management
47
Jacobs Levy Equity Management
New Jersey
$142K +$142K +535 New
CSS
48
Cubist Systematic Strategies
Connecticut
$131K +$131K +494 New
Two Sigma Investments
49
Two Sigma Investments
New York
$127K +$127K +481 New
Royal Bank of Canada
50
Royal Bank of Canada
Ontario, Canada
$124K +$122K +461 +5,763%
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