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Spyre Therapeutics
SYRE

Overview Fund Activity

107 hedge funds and large institutions have $1.18B invested in Spyre Therapeutics in 2024 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 47 increasing their positions, 17 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
107
Holders Change
+4
Holders Change %
+3.88%
% of All Funds
1.56%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
29
Increased
47
Reduced
17
Closed
24
Calls
$61K
Puts
$35K
Net Calls
+$26K
Net Calls Change
-$50K

Top Buyers

1
FFM
Fairmount Funds Management
Pennsylvania
+$85.6M
2
B
Braidwell
Connecticut
+$47M
3
BlackRock
BlackRock
New York
+$43.4M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$33.3M
5
State Street
State Street
Massachusetts
+$30M

Top Sellers

1
YF
Yu Fan
-$16.4M
2
Millennium Management
Millennium Management
New York
-$12.1M
3
CAM
Cormorant Asset Management
Massachusetts
-$9.48M
4
Marshall Wace
Marshall Wace
United Kingdom
-$6.14M
5
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$3.85M
Name Holding Trade Value Shares
Change 		Shares
Change %
FTM
26
First Turn Management
California
$10.9M – – –
DGM
27
Darwin Global Management
Jersey
$10.3M -$481K -21,160 -4%
Morgan Stanley
28
Morgan Stanley
New York
$9.61M +$8.41M +357,665 +699%
Pictet Asset Management
29
Pictet Asset Management
Switzerland
$9.09M +$9.09M +386,617 New
T. Rowe Price Associates
30
T. Rowe Price Associates
Maryland
$7.24M +$5.4M +229,447 +292%
Blackstone Inc
31
Blackstone Inc
New York
$6.89M +$6.42M +273,004 +1,366%
Voloridge Investment Management
32
Voloridge Investment Management
Florida
$6.47M +$2.05M +87,173 +46%
Balyasny Asset Management
33
Balyasny Asset Management
Illinois
$6.41M +$5.65M +240,239 +742%
WP
34
Woodline Partners
California
$6.17M +$3.81M +162,089 +161%
GTC
35
Ghost Tree Capital
New York
$5.88M +$3.53M +150,237 +150%
APM
36
Avidity Partners Management
Texas
$4.58M +$4.58M +195,000 New
Bank of America
37
Bank of America
North Carolina
$4.49M +$3.64M +154,837 +426%
Walleye Capital
38
Walleye Capital
New York
$3.55M +$925K +39,342 +35%
SC
39
Stempoint Capital
New York
$3.54M +$2.07M +88,197 +142%
SFM
40
Soros Fund Management
New York
$3.41M +$2.7M +114,962 +383%
AC
41
Armistice Capital
New York
$3.2M +$3.2M +136,000 New
GPP
42
Great Point Partners
Connecticut
$3.16M +$226K +9,612 +8%
Bank of New York Mellon
43
Bank of New York Mellon
New York
$2.77M +$2.62M +111,636 +1,845%
Nuveen Asset Management
44
Nuveen Asset Management
Illinois
$2.75M +$2.75M +117,140 New
HS
45
HighVista Strategies
Massachusetts
$2.67M -$960K -40,831 -26%
SCM
46
Suvretta Capital Management
New York
$2.52M -$1.3M -55,085 -34%
CS
47
Candriam SCA
Luxembourg
$2.47M – – –
IHAM
48
Integral Health Asset Management
New York
$2.35M – – –
Charles Schwab
49
Charles Schwab
California
$2.31M +$1.96M +83,181 +555%
JFG
50
Jefferies Financial Group
New York
$2.29M +$2.29M +97,573 New
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