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Integral Health Asset Management’s Spyre Therapeutics SYRE Stock Holding History

Integral Health Asset Management’s Portfolio SYRE Stock Details SYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$28.9M Buy
+325,000
New +$23.7M 1.14% 26
2024
Q3 		– Sell
-100,000
Closed -$2.35M – 97
2024
Q2 		$2.35M Hold
100,000
– – 0.22% 70
2024
Q1 		$3.79M Buy
+100,000
New +$2.9M 0.35% 70

Other funds holding SYRE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.38T AUM 44.17% 1-Year Est. Return
VA
VR Adviser New York $3.3B AUM 525.74% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

Integral Health Asset Management's SYRE Position: Q2 2026 in Review

Integral Health Asset Management opened a new position in Spyre Therapeutics (SYRE) in Q2 2026: 325,000 shares worth $28.9M. The stake represents 1.14% of the portfolio and ranks #26 among its holdings. This is a return to the name: Integral Health Asset Management previously reported a position in SYRE as recently as Q2 2024.

Integral Health Asset Management first reported a position in SYRE in Q1 2024 and has held it in 3 quarters since. 266 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • Integral Health Asset Management held 325,000 shares of Spyre Therapeutics worth $28.9M as of Q2 2026.
  • Spyre Therapeutics was a new Integral Health Asset Management position in Q2 2026.
  • Spyre Therapeutics made up 1.14% of Integral Health Asset Management's portfolio in Q2 2026, its #26 holding.
  • Integral Health Asset Management first reported a position in Spyre Therapeutics in Q1 2024 and has held it in 3 quarters since.
  • 266 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on Integral Health Asset Management's 13F filing for Q2 2026, filed 14 Aug 2026.