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Spyre Therapeutics

85 hedge funds and large institutions have $189M invested in Spyre Therapeutics in 2021 Q4 according to their latest regulatory filings, with 18 funds opening new positions, 26 increasing their positions, 22 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
85
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$263K
Puts
$248K
Net Calls
Net Calls Change

Top Buyers

1 +$6.16M
2 +$4.01M
3 +$1.96M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$946K
5
CAM
ClariVest Asset Management
California
+$832K

Top Sellers

1 -$11.9M
2 -$5.03M
3 -$1.64M
4
ACM
Altium Capital Management
New York
-$1.5M
5
Marshall Wace
Marshall Wace
United Kingdom
-$1.3M
Name Holding Trade Value Shares
Change
Change in
Stake
26
$1.18M
27
$1.17M
28
$1.14M
29
$1.08M
30
$932K
31
$905K
32
$832K
33
$757K
34
$684K
35
$653K
36
$649K
37
$620K
38
$532K
39
$503K
40
$473K
41
$364K
42
$363K
43
$306K
44
$271K
45
$266K
46
$256K
47
$233K
48
$199K
49
$197K
50
$181K