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Spyre Therapeutics
SYRE

Overview Fund Activity

31 hedge funds and large institutions have $42.9M invested in Spyre Therapeutics in 2017 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 11 increasing their positions, 3 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
31
Holders Change
-1
Holders Change %
-3.13%
% of All Funds
0.7%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
4
Increased
11
Reduced
3
Closed
5
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
NCM
Nantahala Capital Management
Connecticut
+$1.31M
2
Vanguard Group
Vanguard Group
Pennsylvania
+$600K
3
Dimensional Fund Advisors
Dimensional Fund Advisors
Texas
+$123K
4
Renaissance Technologies
Renaissance Technologies
New York
+$105K
5
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
+$85K

Top Sellers

1
SCM
Sio Capital Management
New York
-$639K
2
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$576K
3
NI
Numeric Investors
Massachusetts
-$190K
4
SIM
Spark Investment Management
New York
-$165K
5
OAM
Oxford Asset Management
United Kingdom
-$86K
Name Holding Trade Value Shares
Change 		Shares
Change %
JPMorgan Chase & Co
26
JPMorgan Chase & Co
New York
$33K +$31.9K +234 +2,925%
Morgan Stanley
27
Morgan Stanley
New York
$16K – – –
Bank of Montreal
28
Bank of Montreal
Ontario, Canada
$16K +$15.9K +119 +11,900%
Macquarie Group
29
Macquarie Group
Australia
$9K +$9K +70 New
UBS Group
30
UBS Group
Switzerland
$7K -$3.3K -25 -32%
IA
31
IFP Advisors
Florida
$3K -$14.1K -94 -82%
SCM
32
Sio Capital Management
New York
– -$639K -5,183 Closed
Alyeska Investment Group
33
Alyeska Investment Group
Illinois
– -$576K -4,677 Closed
NI
34
Numeric Investors
Massachusetts
– -$190K -1,600 Closed
OAM
35
Oxford Asset Management
United Kingdom
– -$86K -713 Closed
VF
36
Virtu Financial
New York
– -$64K -517 Closed
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