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Spyre Therapeutics

85 hedge funds and large institutions have $189M invested in Spyre Therapeutics in 2021 Q4 according to their latest regulatory filings, with 18 funds opening new positions, 26 increasing their positions, 22 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
85
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$263K
Puts
$248K
Net Calls
Net Calls Change

Top Buyers

1 +$6.16M
2 +$4.01M
3 +$1.96M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$946K
5
CAM
ClariVest Asset Management
California
+$832K

Top Sellers

1 -$11.9M
2 -$5.03M
3 -$1.64M
4
ACM
Altium Capital Management
New York
-$1.5M
5
Marshall Wace
Marshall Wace
United Kingdom
-$1.3M
Name Holding Trade Value Shares
Change
Change in
Stake
76
$18K
77
$16K
78
$14K
79
$14K
80
$6K
81
$5K
82
$1K
83
$1K
84
$96
85
86
87
88
89
90
91
92
93