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Spyre Therapeutics
SYRE

Overview Fund Activity

66 hedge funds and large institutions have $25.4M invested in Spyre Therapeutics in 2022 Q2 according to their latest regulatory filings, with 13 funds opening new positions, 21 increasing their positions, 17 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
66
Holders Change
-17
Holders Change %
-20.48%
% of All Funds
1.12%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
13
Increased
21
Reduced
17
Closed
28
Calls
$23K
Puts
–
Net Calls
+$23K
Net Calls Change
+$20K

Top Buyers

1
SCM
1
Sio Capital Management
New York
$2.36M
2
GPP
2
Great Point Partners
Connecticut
$1.26M
3
BCLSI
3
Bain Capital Life Sciences Investors
Massachusetts
$2.7M
4
PAMS
4
Pictet Asset Management (Switzerland)
Switzerland
$2.47M
5
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$758K

Top Sellers

1
LCM
1
Laurion Capital Management
New York
$0
2
Deutsche Bank
2
Deutsche Bank
Germany
$0
3
Jacobs Levy Equity Management
3
Jacobs Levy Equity Management
New Jersey
$0
4
BlackRock
4
BlackRock
New York
$540K
5
Nuveen Asset Management
5
Nuveen Asset Management
Illinois
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
UOTTAIMCU
26
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$124K – – –
A
27
Abingworth
United Kingdom
$121K – – –
Two Sigma Advisers
28
Two Sigma Advisers
New York
$117K +$35.5K +2,816 +44%
Citadel Advisors
29
Citadel Advisors
Florida
$115K +$77.8K +6,151 +209%
State Street
30
State Street
Massachusetts
$80K -$316K -25,122 -80%
E
31
Ergoteles
New York
$74K +$74K +5,888 New
YF
32
Yu Fan
$57K – – –
FSA
33
Franklin Street Advisors
North Carolina
$53K – – –
RWM
34
Ritholtz Wealth Management
New York
$39K – – –
William Blair & Company
35
William Blair & Company
Illinois
$39K – – –
UBS Group
36
UBS Group
Switzerland
$39K +$5.85K +461 +18%
Northern Trust
37
Northern Trust
Illinois
$35K -$134K -10,582 -79%
Susquehanna International Group
38
Susquehanna International Group
Pennsylvania
$33K +$33K +2,608 New
IA
39
IFP Advisors
Florida
$29K – – –
BCM
40
Bridgeway Capital Management
Texas
$25K -$38.2K -2,974 -60%
Qube Research & Technologies (QRT)
41
Qube Research & Technologies (QRT)
United Kingdom
$21K +$21K +1,638 New
Franklin Resources
42
Franklin Resources
California
$16K -$7.61K -597 -32%
VF
43
Virtu Financial
New York
$16K +$16K +1,246 New
Bank of New York Mellon
44
Bank of New York Mellon
New York
$13K -$68.6K -5,301 -84%
BC
45
BIT Capital
Germany
$12.6K – – –
LP
46
LMR Partners
United Kingdom
$10K +$10K +769 New
SG Americas Securities
47
SG Americas Securities
New York
$9K +$9K +713 New
TRCT
48
Tower Research Capital (TRC)
New York
$8K -$3.25K -255 -29%
Man Group
49
Man Group
United Kingdom
$8K – – –
SSA
50
Schonfeld Strategic Advisors
New York
$5K +$5K +404 New
1
2
3 4