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Spyre Therapeutics

77 hedge funds and large institutions have $322M invested in Spyre Therapeutics in 2021 Q3 according to their latest regulatory filings, with 10 funds opening new positions, 23 increasing their positions, 23 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
77
Holders Change
-1
Holders Change %
-1.28%
% of All Funds
1.35%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
10
Increased
23
Reduced
23
Closed
10
Calls
$90K
Puts
Net Calls
+$90K
Net Calls Change
-$122K
Name Holding Trade Value Shares
Change
Shares
Change %
LPC
26
Lion Point Capital
New York
$2.39M
Assenagon Asset Management
27
Assenagon Asset Management
Luxembourg
$2.12M -$119K -600 -5%
UOTTAIMCU
28
University of Texas/Texas AM Investment Management Co (UTIMCO)
Texas
$1.95M -$190K -956 -9%
A
29
Abingworth
United Kingdom
$1.91M
Morgan Stanley
30
Morgan Stanley
New York
$1.54M -$10.3K -52 -0.7%
Nuveen Asset Management
31
Nuveen Asset Management
Illinois
$1.34M -$34.5K -185 -3%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$1.27M +$96.2K +484 +8%
YF
33
Yu Fan
$891K
AA
34
AlphaCentric Advisors
Puerto Rico
$875K +$139K +700 +19%
FSA
35
Franklin Street Advisors
North Carolina
$824K
Renaissance Technologies
36
Renaissance Technologies
New York
$797K +$394K +1,981 +98%
Charles Schwab
37
Charles Schwab
California
$791K -$50.1K -252 -6%
RWM
38
Ritholtz Wealth Management
New York
$608K -$780K -3,926 -56%
UBS Group
39
UBS Group
Switzerland
$431K +$17.1K +86 +4%
RhumbLine Advisers
40
RhumbLine Advisers
Massachusetts
$430K +$11.7K +59 +3%
William Blair & Company
41
William Blair & Company
Illinois
$415K
PPA
42
Parametric Portfolio Associates
Washington
$359K +$95.1K +478 +36%
AG
43
Algert Global
California
$293K -$37.4K -188 -11%
D.E. Shaw & Co
44
D.E. Shaw & Co
New York
$227K -$139K -699 -38%
SG Americas Securities
45
SG Americas Securities
New York
$227K +$227K +1,143 New
AllianceBernstein
46
AllianceBernstein
Tennessee
$204K
Bank of America
47
Bank of America
North Carolina
$204K +$43.1K +217 +27%
Manulife (Manufacturers Life Insurance)
48
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$201K -$9.52K -48 -5%
Deutsche Bank
49
Deutsche Bank
Germany
$185K -$5.97K -30 -3%
AIG
50
American International Group
New York
$176K -$4.18K -21 -2%