ALPS Medical Breakthroughs ETF
SBIO
61 hedge funds and large institutions have $44.6M invested in ALPS Medical Breakthroughs ETF in 2026 Q1 according to their latest regulatory filings, with 13 funds opening new positions, 16 increasing their positions, 14 reducing their positions, and 8 closing their positions.
63% more first-time investments, than exits
New positions opened: 13 | Existing positions closed: 8
14% more repeat investments, than reductions
Existing positions increased: 16 | Existing positions reduced: 14
3% more funds holding
Funds holding: 59 → 61 (+2)
58.71% less ownership
Funds ownership: 92.42% → 33.71% (-59%)
71% less capital inflows, than outflows
Capital inflows: $14.6M | Capital outflows: $50.2M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
+$3.09M |
| 2 |
Bank of America
Charlotte,
North Carolina
|
+$1.94M |
| 3 |
CIS
Connors Investor Services
Wyomissing,
Pennsylvania
|
+$1.76M |
| 4 |
Wells Fargo
San Francisco,
California
|
+$1.45M |
| 5 |
GS
GTS Securities
Miami,
Florida
|
+$968K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PF
Phoenix Financial
Givatayim,
Israel
|
-$38.3M |
| 2 |
DIM
Delta Investment Management
San Francisco,
California
|
-$6.11M |
| 3 |
Raymond James Financial
St Petersburg,
Florida
|
-$2.15M |
| 4 |
Two Sigma Investments
New York
|
-$1.7M |
| 5 |
Morgan Stanley
New York
|
-$579K |
SBIO Hedge Fund Activity: Q1 2026 in Review
61 of the 8,210 institutional investors tracked by Wall St. Rank reported a position in ALPS Medical Breakthroughs ETF (SBIO) for Q1 2026, worth a combined $44.6M — down 44% from $79.2M a quarter earlier.
Buyers outnumbered sellers: 13 funds opened new SBIO positions and 8 closed out — a net gain of 5 holders — while 16 added to existing stakes and 14 trimmed.
The largest buyer was Susquehanna International Group, opening a new position worth an estimated $3.09M. The largest seller was Phoenix Financial, exiting entirely with an estimated $38.3M sold.
- 61 institutional investors held ALPS Medical Breakthroughs ETF (SBIO) as of Q1 2026, up from 59 in Q4 2025.
- Funds reported $44.6M of ALPS Medical Breakthroughs ETF stock for Q1 2026, down 44% quarter-over-quarter.
- 13 funds opened new ALPS Medical Breakthroughs ETF positions in Q1 2026 and 8 closed out, a net change of +5 holders.
- The largest ALPS Medical Breakthroughs ETF buyer in Q1 2026 was Susquehanna International Group, an estimated $3.09M added.
- The largest ALPS Medical Breakthroughs ETF seller in Q1 2026 was Phoenix Financial, an estimated $38.3M sold.
Based on aggregated 13F filings for Q1 2026.