ALPS Medical Breakthroughs ETF
SBIO
39 hedge funds and large institutions have $74.7M invested in ALPS Medical Breakthroughs ETF in 2025 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 5 increasing their positions, 11 reducing their positions, and 5 closing their positions.
60% more first-time investments, than exits
New positions opened: 8 | Existing positions closed: 5
8% more funds holding
Funds holding: 36 → 39 (+3)
0% more capital invested
Capital invested by funds: $74.3M → $74.7M (+$356K)
1.38% less ownership
Funds ownership: 104.33% → 102.96% (-1.4%)
55% less repeat investments, than reductions
Existing positions increased: 5 | Existing positions reduced: 11
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
VF
Virtu Financial
New York
|
+$575K |
| 2 |
SIAP
Sterling Investment Advisors (Pennsylvania)
Berwyn,
Pennsylvania
|
+$278K |
| 3 |
MWM
Moran Wealth Management
Naples,
Florida
|
+$248K |
| 4 |
IFG
Independent Financial Group
San Diego,
California
|
+$189K |
| 5 |
Wells Fargo
San Francisco,
California
|
+$67.8K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
DC
Davenport & Co
Richmond,
Virginia
|
-$6.88M |
| 2 |
GS
GTS Securities
New York
|
-$971K |
| 3 |
Citadel Advisors
Miami,
Florida
|
-$713K |
| 4 |
UBS Group
Zurich,
Switzerland
|
-$682K |
| 5 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$627K |
SBIO Hedge Fund Activity: Q3 2025 in Review
39 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in ALPS Medical Breakthroughs ETF (SBIO) for Q3 2025, worth a combined $74.7M — up 0.48% from $74.3M a quarter earlier.
Buyers outnumbered sellers: 8 funds opened new SBIO positions and 5 closed out — a net gain of 3 holders — while 5 added to existing stakes and 11 trimmed.
The largest buyer was Virtu Financial, opening a new position worth an estimated $575K. The largest seller was Davenport & Co, cutting an estimated $6.88M.
- 39 institutional investors held ALPS Medical Breakthroughs ETF (SBIO) as of Q3 2025, up from 36 in Q2 2025.
- Funds reported $74.7M of ALPS Medical Breakthroughs ETF stock for Q3 2025, up 0.48% quarter-over-quarter.
- 8 funds opened new ALPS Medical Breakthroughs ETF positions in Q3 2025 and 5 closed out, a net change of +3 holders.
- The largest ALPS Medical Breakthroughs ETF buyer in Q3 2025 was Virtu Financial, an estimated $575K added.
- The largest ALPS Medical Breakthroughs ETF seller in Q3 2025 was Davenport & Co, an estimated $6.88M sold.
Based on aggregated 13F filings for Q3 2025.