ALPS Medical Breakthroughs ETF
SBIO
34 hedge funds and large institutions have $73M invested in ALPS Medical Breakthroughs ETF in 2025 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 4 increasing their positions, 13 reducing their positions, and 6 closing their positions.
467% more call options, than puts
Call options by funds: $34K | Put options by funds: $6K
50.99% more ownership
Funds ownership: 47.46% → 98.45% (+51%)
49% more capital invested
Capital invested by funds: $49.1M → $73M (+$23.9M)
3% less funds holding
Funds holding: 35 → 34 (-1)
17% less first-time investments, than exits
New positions opened: 5 | Existing positions closed: 6
69% less repeat investments, than reductions
Existing positions increased: 4 | Existing positions reduced: 13
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PF
Phoenix Financial
Givatayim,
Israel
|
+$46.3M |
| 2 |
GS
GWN Securities
Palm Beach Gardens,
Florida
|
+$1.75M |
| 3 |
Bank of America
Charlotte,
North Carolina
|
+$236K |
| 4 |
RF
Rossby Financial
Melbourne,
Florida
|
+$164K |
| 5 |
SFS
Strategic Financial Services
Utica,
New York
|
+$68.4K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Morgan Stanley
New York
|
-$1.01M |
| 2 |
DC
Davenport & Co
Richmond,
Virginia
|
-$675K |
| 3 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$565K |
| 4 |
GS
GTS Securities
New York
|
-$537K |
| 5 |
UBS Group
Zurich,
Switzerland
|
-$445K |
SBIO Hedge Fund Activity: Q1 2025 in Review
34 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in ALPS Medical Breakthroughs ETF (SBIO) for Q1 2025, worth a combined $73M — up 49% from $49.1M a quarter earlier.
Sellers outnumbered buyers: 6 funds closed out of SBIO and 5 opened new positions — a net loss of 1 holder — while 13 trimmed existing stakes and 4 added.
The largest buyer was Phoenix Financial, opening a new position worth an estimated $46.3M. The largest seller was Morgan Stanley, cutting an estimated $1.01M.
- 34 institutional investors held ALPS Medical Breakthroughs ETF (SBIO) as of Q1 2025, down from 35 in Q4 2024.
- Funds reported $73M of ALPS Medical Breakthroughs ETF stock for Q1 2025, up 49% quarter-over-quarter.
- 5 funds opened new ALPS Medical Breakthroughs ETF positions in Q1 2025 and 6 closed out, a net change of -1 holder.
- The largest ALPS Medical Breakthroughs ETF buyer in Q1 2025 was Phoenix Financial, an estimated $46.3M added.
- The largest ALPS Medical Breakthroughs ETF seller in Q1 2025 was Morgan Stanley, an estimated $1.01M sold.
Based on aggregated 13F filings for Q1 2025.