ALPS Medical Breakthroughs ETF
SBIO
36 hedge funds and large institutions have $74.3M invested in ALPS Medical Breakthroughs ETF in 2025 Q2 according to their latest regulatory filings, with 5 funds opening new positions, 4 increasing their positions, 12 reducing their positions, and 3 closing their positions.
67% more first-time investments, than exits
New positions opened: 5 | Existing positions closed: 3
5.89% more ownership
Funds ownership: 98.45% → 104.33% (+5.9%)
6% more funds holding
Funds holding: 34 → 36 (+2)
2% more capital invested
Capital invested by funds: $73M → $74.3M (+$1.32M)
67% less repeat investments, than reductions
Existing positions increased: 4 | Existing positions reduced: 12
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
GS
GTS Securities
New York
|
+$1.19M |
| 2 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
+$747K |
| 3 |
SFS
Strategic Financial Services
Utica,
New York
|
+$538K |
| 4 |
MWM
Moran Wealth Management
Naples,
Florida
|
+$285K |
| 5 |
Citadel Advisors
Miami,
Florida
|
+$262K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Bank of America
Charlotte,
North Carolina
|
-$2.46M |
| 2 |
DC
Davenport & Co
Richmond,
Virginia
|
-$1.79M |
| 3 |
GS
GWN Securities
Palm Beach Gardens,
Florida
|
-$1.51M |
| 4 |
Morgan Stanley
New York
|
-$487K |
| 5 |
NAM
NTV Asset Management
Charleston,
West Virginia
|
-$196K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
26
US Bancorp
Minneapolis,
Minnesota
| $30.1K | – | – | – |
|
27
Osaic Holdings
Scottsdale,
Arizona
| $17.7K | -$4.21K | -147 | -20% |
|
|
IA
28
IFP Advisors
Tampa,
Florida
| $9.98K | – | – | – |
|
29
PNC Financial Services Group
Pittsburgh,
Pennsylvania
| $6.01K | +$5.72K | +200 | New |
|
|
ADL
30
Asset Dedication LLC
San Francisco,
California
| $5.02K | – | – | – |
|
|
SC
31
SouthState Corp
Winter Haven,
Florida
| $4.21K | – | – | – |
|
|
SL
32
Salomon & Ludwin
Richmond,
Virginia
| $3.06K | – | – | – |
|
33
Bank of Montreal
Toronto,
Ontario, Canada
| $3.01K | – | – | – |
|
|
FCAS
34
First Command Advisory Services
Fort Worth,
Texas
| $3.01K | – | – | – |
|
|
AFG
35
Albion Financial Group
Salt Lake City,
Utah
| $361 | – | – | – |
|
|
GS
36
GWN Securities
Palm Beach Gardens,
Florida
| – | -$1.51M | -55,500 | Closed |
|
37
Comerica Bank
Dallas,
Texas
| – | -$23.1K | -810 | Closed |
|
|
S
38
SignatureFD
Atlanta,
Georgia
| – | -$5.7K | -200 | Closed |
|
SBIO Hedge Fund Activity: Q2 2025 in Review
36 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in ALPS Medical Breakthroughs ETF (SBIO) for Q2 2025, worth a combined $74.3M — up 1.8% from $73M a quarter earlier.
Buyers outnumbered sellers: 5 funds opened new SBIO positions and 3 closed out — a net gain of 2 holders — while 4 added to existing stakes and 12 trimmed.
The largest buyer was GTS Securities, adding an estimated $1.19M. The largest seller was Bank of America, cutting an estimated $2.46M.
- 36 institutional investors held ALPS Medical Breakthroughs ETF (SBIO) as of Q2 2025, up from 34 in Q1 2025.
- Funds reported $74.3M of ALPS Medical Breakthroughs ETF stock for Q2 2025, up 1.8% quarter-over-quarter.
- 5 funds opened new ALPS Medical Breakthroughs ETF positions in Q2 2025 and 3 closed out, a net change of +2 holders.
- The largest ALPS Medical Breakthroughs ETF buyer in Q2 2025 was GTS Securities, an estimated $1.19M added.
- The largest ALPS Medical Breakthroughs ETF seller in Q2 2025 was Bank of America, an estimated $2.46M sold.
Based on aggregated 13F filings for Q2 2025.