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UOC

UBS O'Connor Portfolio holdings

AUM $3.38B
1-Year Est. Return 63.08%
This Fund
S&P 500
This Quarter Est. Return
+12.69%
1 Year Est. Return
+63.08%
3 Year Est. Return
+180.99%
5 Year Est. Return
+483.22%
10 Year Est. Return
+2,128.59%
AUM
$3.05B
AUM Growth
-$542M
Cap. Flow
-$855M
Cap. Flow %
-28%
Top 10 Hldgs %
68.02%
Holding
472
New
104
Increased
41
Reduced
44
Closed
200

Top Buys

1
VRNA
Verona Pharma
VRNA
+$447M
2
CYBR
CyberArk
CYBR
+$424M
3
IPG
Interpublic Group of Companies
IPG
+$96.3M
4
COOP
Mr. Cooper
COOP
+$67.2M
5
AL
Air Lease Corp
AL
+$48.8M

Top Sells

1
WBA
Walgreens Boots Alliance
WBA
+$288M
2
SKX
Skechers
SKX
+$227M
3
BPMC
Blueprint Medicines
BPMC
+$220M
4
CHX
ChampionX
CHX
+$187M
5
ANSS
Ansys
ANSS
+$173M

Sector Composition

1 Technology 23.63%
2 Healthcare 16.98%
3 Communication Services 12.23%
4 Financials 11.14%
5 Consumer Staples 9.63%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
INSP icon
351
Inspire Medical Systems
INSP
$1.49B
– –
-9,522
Closed -$1.24M
INSP icon
352
PUT
Inspire Medical Systems
INSP
$1.49B
– –
-10,000
Closed -$85.5K
IONS icon
353
Ionis Pharmaceuticals
IONS
$9.03B
– –
-81,251
Closed -$3.21M
IQV icon
354
IQVIA
IQV
$35.1B
– –
-10,275
Closed -$1.62M
IR icon
355
Ingersoll Rand
IR
$33.2B
– –
-116,100
Closed -$9.66M
IRM icon
356
PUT
Iron Mountain
IRM
$36.2B
– –
-25,000
Closed -$70K
IRON icon
357
Disc Medicine
IRON
$2.81B
– –
-12,317
Closed -$652K
IRTC icon
358
iRhythm Holdings
IRTC
$3.79B
– –
-7,993
Closed -$1.23M
ITGR icon
359
Integer Holdings
ITGR
$3.38B
– –
-21,375
Closed -$2.63M
IWM icon
360
CALL
iShares Russell 2000 ETF
IWM
$82.6B
– –
-105,000
Closed -$288K
IWM icon
361
iShares Russell 2000 ETF
IWM
$82.6B
– –
-25,000
Closed -$5.39M
JBLU icon
362
CALL
JetBlue
JBLU
$2.1B
– –
-400,000
Closed -$22K
JNPR
363
DELISTED
Juniper Networks
JNPR
– –
-3,000,000
Closed -$120M
KALA icon
364
KALA BIO
KALA
$15.7M
– –
-2,771
Closed -$660K
KALV
365
DELISTED
KalVista Pharmaceuticals
KALV
– –
-79,460
Closed -$898K
KIDS icon
366
OrthoPediatrics
KIDS
$523M
– –
-65,866
Closed -$1.41M
KNSA icon
367
Kiniksa Pharmaceuticals
KNSA
$4.7B
– –
-37,602
Closed -$1.04M
KROS icon
368
Keros Therapeutics
KROS
$210M
– –
-37,891
Closed -$506K
LRMR icon
369
Larimar Therapeutics
LRMR
$381M
– –
-307,198
Closed -$888K
LX
370
LexinFintech Holdings
LX
$250M
– –
-1,149,107
Closed -$8.29M
MBLY icon
371
Mobileye
MBLY
$7.55B
– –
-30,000
Closed -$539K
MEOH icon
372
Methanex
MEOH
$4.11B
– –
-76,000
Closed -$2.52M
MIRM icon
373
Mirum Pharmaceuticals
MIRM
$7.16B
– –
-21,409
Closed -$1.09M
MLYS icon
374
Mineralys Therapeutics
MLYS
$2.39B
– –
-79,723
Closed -$1.08M
MRNA icon
375
CALL
Moderna
MRNA
$25.1B
– –
-35,000
Closed -$23.4K
13 14
15
16 17

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SAG
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ACI
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TCOV
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RCM
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CGL
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UBS O'Connor's Q3 2025 Portfolio in Review

As of Q3 2025, UBS O'Connor held 472 positions worth $3.05B, down 15% from $3.6B the previous quarter. Its ten largest holdings account for 68% of the portfolio.

UBS O'Connor withdrew a net $855M in Q3 2025, closing 200 positions and reducing 44 holdings. Its most notable exit was Walgreens Boots Alliance, an estimated $288M position sold in full.

By sector, the portfolio is most concentrated in Technology at 24% of assets, up from 15% a quarter earlier, followed by Healthcare and Communication Services.

Against the trend, UBS O'Connor opened a new position in Verona Pharma worth $457M.

  • UBS O'Connor's largest Q3 2025 buy was Verona Pharma: 4,283,462 shares worth $457M.
  • UBS O'Connor added most to Interpublic Group of Companies in Q3 2025, an estimated $96.3M increase.
  • UBS O'Connor's biggest Q3 2025 reduction was Kellanova, cutting an estimated $110M.
  • UBS O'Connor fully exited Walgreens Boots Alliance in Q3 2025, selling an estimated $288M.
  • UBS O'Connor's ten largest holdings make up 68% of its $3.05B portfolio in Q3 2025.
  • UBS O'Connor opened 104 new positions and closed 200 in Q3 2025.
  • UBS O'Connor's portfolio value fell 15% quarter-over-quarter to $3.05B.

Based on UBS O'Connor's 13F filing for Q3 2025, filed 14 Nov 2025.