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UOC

UBS O'Connor Portfolio holdings

AUM $3.76B
1-Year Est. Return 62.41%
This Fund
S&P 500
This Quarter Est. Return
+13.49%
1 Year Est. Return
+62.41%
3 Year Est. Return
+179.84%
5 Year Est. Return
+371.69%
10 Year Est. Return
+1,534.25%
AUM
$3.34B
AUM Growth
-$346M
Cap. Flow
-$728M
Cap. Flow %
-21.78%
Top 10 Hldgs %
68.3%
Holding
475
New
106
Increased
41
Reduced
44
Closed
201

Top Buys

Rank Stock Value
1
VRNA
Verona Pharma
VRNA
+$447M
2
CYBR
CyberArk
CYBR
+$424M
3
GTLS
Chart Industries
GTLS
+$243M
4
IPG
Interpublic Group of Companies
IPG
+$96.3M
5
COOP
Mr. Cooper
COOP
+$67.2M

Top Sells

Rank Stock Value
1
WBA
Walgreens Boots Alliance
WBA
+$288M
2
SKX
Skechers
SKX
+$227M
3
BPMC
Blueprint Medicines
BPMC
+$220M
4
CHX
ChampionX
CHX
+$187M
5
ANSS
Ansys
ANSS
+$173M

Sector Composition

Rank Sector Weight
1 Technology 21.6%
2 Industrials 16.01%
3 Healthcare 15.52%
4 Communication Services 12.09%
5 Financials 10.18%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
INSM icon
351
Insmed
INSM
$27.6B
– –
-26,301
Closed -$2.65M
INSM icon
352
PUT
Insmed
INSM
$27.6B
– –
-27,000
Closed -$138K
INSP icon
353
Inspire Medical Systems
INSP
$1.82B
– –
-9,522
Closed -$1.24M
INSP icon
354
PUT
Inspire Medical Systems
INSP
$1.82B
– –
-10,000
Closed -$85.5K
IONS icon
355
Ionis Pharmaceuticals
IONS
$9.65B
– –
-81,251
Closed -$3.21M
IQV icon
356
IQVIA
IQV
$44.1B
– –
-10,275
Closed -$1.62M
IR icon
357
Ingersoll Rand
IR
$29.6B
– –
-116,100
Closed -$9.66M
IRM icon
358
PUT
Iron Mountain
IRM
$34.8B
– –
-25,000
Closed -$70K
IRON icon
359
Disc Medicine
IRON
$3.04B
– –
-12,317
Closed -$652K
IRTC icon
360
iRhythm Holdings
IRTC
$4.06B
– –
-7,993
Closed -$1.23M
ITGR icon
361
Integer Holdings
ITGR
$4.3B
– –
-21,375
Closed -$2.63M
IWM icon
362
CALL
iShares Russell 2000 ETF
IWM
$81.2B
– –
-105,000
Closed -$288K
IWM icon
363
iShares Russell 2000 ETF
IWM
$81.2B
– –
-25,000
Closed -$5.39M
JBLU icon
364
CALL
JetBlue
JBLU
$1.75B
– –
-400,000
Closed -$22K
JNPR
365
DELISTED
Juniper Networks
JNPR
– –
-3,000,000
Closed -$120M
KALA icon
366
KALA BIO
KALA
$9.81M
– –
-2,771
Closed -$660K
KALV
367
DELISTED
KalVista Pharmaceuticals
KALV
– –
-79,460
Closed -$898K
KIDS icon
368
OrthoPediatrics
KIDS
$585M
– –
-65,866
Closed -$1.41M
KNSA icon
369
Kiniksa Pharmaceuticals
KNSA
$6.08B
– –
-37,602
Closed -$1.04M
KROS icon
370
Keros Therapeutics
KROS
$224M
– –
-37,891
Closed -$506K
LBRDK
371
DELISTED
Liberty Broadband Class C
LBRDK
– –
-919,381
Closed -$90.4M
LRMR icon
372
Larimar Therapeutics
LRMR
$398M
– –
-307,198
Closed -$888K
LX
373
LexinFintech Holdings
LX
$145M
– –
-1,149,107
Closed -$8.29M
MBLY icon
374
Mobileye
MBLY
$7.28B
– –
-30,000
Closed -$539K
MEOH icon
375
Methanex
MEOH
$4.54B
– –
-76,000
Closed -$2.52M
13 14
15
16 17

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ACI
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RC
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A
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CGL
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CB
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JCM
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MPM
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UBS O'Connor's Q3 2025 Portfolio in Review

As of Q3 2025, UBS O'Connor held 475 positions worth $3.34B, down 9.4% from $3.69B the previous quarter. Its ten largest holdings account for 68% of the portfolio.

UBS O'Connor withdrew a net $728M in Q3 2025, closing 201 positions and reducing 44 holdings. Its most notable exit was Walgreens Boots Alliance, an estimated $288M position sold in full.

By sector, the portfolio is most concentrated in Technology at 22% of assets, up from 14% a quarter earlier, followed by Industrials and Healthcare.

Against the trend, UBS O'Connor opened a new position in Verona Pharma worth $457M.

  • UBS O'Connor's largest Q3 2025 buy was Verona Pharma: 4,283,462 shares worth $457M.
  • UBS O'Connor added most to Interpublic Group of Companies in Q3 2025, an estimated $96.3M increase.
  • UBS O'Connor's biggest Q3 2025 reduction was Kellanova, cutting an estimated $110M.
  • UBS O'Connor fully exited Walgreens Boots Alliance in Q3 2025, selling an estimated $288M.
  • UBS O'Connor's ten largest holdings make up 68% of its $3.34B portfolio in Q3 2025.
  • UBS O'Connor opened 106 new positions and closed 201 in Q3 2025.
  • UBS O'Connor's portfolio value fell 9.4% quarter-over-quarter to $3.34B.

Based on UBS O'Connor's 13F filing for Q3 2025, filed 14 Nov 2025.