UBS O'Connor Portfolio holdings
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
DAY
Dayforce
DAY
|
+$282M |
| 2 |
CMA
Comerica
CMA
|
+$267M |
| 3 |
RNAM
Avidity Biosciences
RNAM
|
+$240M |
| 4 |
HOLX
Hologic
HOLX
|
+$190M |
| 5 |
EXAS
Exact Sciences
EXAS
|
+$143M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
VRNA
Verona Pharma
VRNA
|
+$457M |
| 2 |
K
Kellanova
K
|
+$290M |
| 3 |
COOP
Mr. Cooper
COOP
|
+$169M |
| 4 |
IPG
Interpublic Group of Companies
IPG
|
+$132M |
| 5 |
INFA
Informatica
INFA
|
+$113M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 28.49% |
| 2 | Healthcare | 21.6% |
| 3 | Financials | 19.98% |
| 4 | Industrials | 8.83% |
| 5 | Communication Services | 8.32% |
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UBS O'Connor's Q4 2025 Portfolio in Review
As of Q4 2025, UBS O'Connor held 345 positions worth $3.38B, up 11% from $3.05B the previous quarter. Its ten largest holdings account for 71% of the portfolio.
UBS O'Connor deployed $113M of net new capital in Q4 2025, opening 79 new positions and adding to 16 existing holdings. Its largest new stake was Dayforce: 4,096,708 shares worth $283M.
By sector, the portfolio is most concentrated in Technology at 28% of assets, up from 24% a quarter earlier, followed by Healthcare and Financials.
On the sell side, the largest reduction was NVIDIA, an estimated $17M trimmed.
- UBS O'Connor's largest Q4 2025 buy was Dayforce: 4,096,708 shares worth $283M.
- UBS O'Connor added most to Air Lease Corp in Q4 2025, an estimated $142M increase.
- UBS O'Connor's biggest Q4 2025 reduction was NVIDIA, cutting an estimated $17M.
- UBS O'Connor fully exited Verona Pharma in Q4 2025, selling an estimated $457M.
- UBS O'Connor's ten largest holdings make up 71% of its $3.38B portfolio in Q4 2025.
- UBS O'Connor opened 79 new positions and closed 110 in Q4 2025.
- UBS O'Connor's portfolio value rose 11% quarter-over-quarter to $3.38B.
Based on UBS O'Connor's 13F filing for Q4 2025, filed 13 Feb 2026.