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UOC

UBS O'Connor Portfolio holdings

AUM $3.76B
1-Year Est. Return 62.41%
This Fund
S&P 500
This Quarter Est. Return
+8.75%
1 Year Est. Return
+62.41%
3 Year Est. Return
+179.84%
5 Year Est. Return
+371.69%
10 Year Est. Return
+1,534.25%
AUM
$3.69B
AUM Growth
-$542M
Cap. Flow
-$781M
Cap. Flow %
-21.18%
Top 10 Hldgs %
56.86%
Holding
480
New
156
Increased
61
Reduced
86
Closed
113

Top Buys

Rank Stock Value
1
SKX
Skechers
SKX
+$207M
2
BPMC
Blueprint Medicines
BPMC
+$176M
3
WBA
Walgreens Boots Alliance
WBA
+$167M
4
DNB
Dun & Bradstreet
DNB
+$122M
5
INFA
Informatica
INFA
+$93.8M

Top Sells

Rank Stock Value
1
DFS
Discover Financial Services
DFS
+$408M
2
ITCI
Intra-Cellular Therapies Inc.
ITCI
+$408M
3
HES
Hess
HES
+$251M
4
BECN
Beacon Roofing Supply, Inc.
BECN
+$195M
5
BERY
Berry Global Group, Inc.
BERY
+$137M

Sector Composition

Rank Sector Weight
1 Healthcare 19.77%
2 Technology 14.28%
3 Consumer Staples 10.98%
4 Energy 9.87%
5 Consumer Discretionary 9.66%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GEV icon
226
GE Vernova
GEV
$251B
$889K 0.02%
+1,680
New +$700K
LRMR icon
227
Larimar Therapeutics
LRMR
$398M
$888K 0.02%
307,198
+127,171
+71% +$294K
QURE icon
228
uniQure
QURE
$3.09B
$885K 0.02%
63,475
-51,414
-45% -$692K
AXGN icon
229
Axogen
AXGN
$2.6B
$884K 0.02%
81,429
-5,999
-7% -$78.6K
MRUS
230
DELISTED
Merus
MRUS
$879K 0.02%
16,704
-7,528
-31% -$354K
SLNO
231
DELISTED
Soleno Therapeutics
SLNO
$868K 0.02%
10,362
-6,660
-39% -$498K
F icon
232
PUT
Ford
F
$58.3B
$868K 0.02%
924,900
+729,400
+373% +$7.43M
ADPT icon
233
Adaptive Biotechnologies
ADPT
$3.87B
$856K 0.02%
73,441
-114,348
-61% -$1.04M
ANAB icon
234
AnaptysBio
ANAB
$1.68B
$855K 0.02%
38,528
-8,523
-18% -$178K
SNDX icon
235
Syndax Pharmaceuticals
SNDX
$1.84B
$847K 0.02%
90,441
+31,003
+52% +$341K
HOG icon
236
PUT
Harley-Davidson
HOG
$2.95B
$841K 0.02%
375,000
+135,000
+56% +$3.21M
PTGX icon
237
Protagonist Therapeutics
PTGX
$9.43B
$803K 0.02%
14,523
+1,183
+9% +$56.8K
RIG icon
238
PUT
Transocean
RIG
$6.53B
$766K 0.02%
883,400
+80,000
+10% +$206K
OFIX icon
239
Orthofix Medical
OFIX
$378M
$753K 0.02%
67,518
-21,541
-24% -$267K
SPKL
240
Spark I Acquisition Corp
SPKL
$100M
$728K 0.02%
66,832
– –
EWTX icon
241
Edgewise Therapeutics
EWTX
$4.68B
$725K 0.02%
55,292
+15,278
+38% +$220K
PTCT icon
242
PTC Therapeutics
PTCT
$5.78B
$711K 0.02%
14,548
-8,805
-38% -$418K
DAWN
243
DELISTED
Day One Biopharmaceuticals
DAWN
$697K 0.02%
107,249
-6,001
-5% -$41.3K
TGTX icon
244
TG Therapeutics
TGTX
$8.57B
$684K 0.02%
+19,000
New +$707K
CGON icon
245
CG Oncology
CGON
$6.62B
$676K 0.02%
+26,000
New +$627K
AXSM icon
246
Axsome Therapeutics
AXSM
$10.8B
$668K 0.02%
+6,400
New +$678K
SKIL icon
247
Skillsoft
SKIL
$61.1M
$666K 0.02%
41,692
– –
KALA icon
248
KALA BIO
KALA
$9.81M
$660K 0.02%
2,771
-647
-19% -$126K
IRON icon
249
Disc Medicine
IRON
$3.04B
$652K 0.02%
12,317
-1,304
-10% -$61.3K
VERA icon
250
Vera Therapeutics
VERA
$2.59B
$646K 0.02%
27,400
+4,875
+22% +$110K
8 9
10
11 12

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ACI
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CGL
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JCM
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MPM
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UBS O'Connor's Q2 2025 Portfolio in Review

As of Q2 2025, UBS O'Connor held 480 positions worth $3.69B, down 13% from $4.23B the previous quarter. Its ten largest holdings account for 57% of the portfolio.

UBS O'Connor withdrew a net $781M in Q2 2025, closing 113 positions and reducing 86 holdings. Its most notable exit was Discover Financial Services, an estimated $408M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 20% of assets, up from 17% a quarter earlier, followed by Technology and Consumer Staples.

Against the trend, UBS O'Connor opened a new position in Skechers worth $227M.

  • UBS O'Connor's largest Q2 2025 buy was Skechers: 3,598,177 shares worth $227M.
  • UBS O'Connor added most to Blueprint Medicines in Q2 2025, an estimated $176M increase.
  • UBS O'Connor's biggest Q2 2025 reduction was Hess, cutting an estimated $251M.
  • UBS O'Connor fully exited Discover Financial Services in Q2 2025, selling an estimated $408M.
  • UBS O'Connor's ten largest holdings make up 57% of its $3.69B portfolio in Q2 2025.
  • UBS O'Connor opened 156 new positions and closed 113 in Q2 2025.
  • UBS O'Connor's portfolio value fell 13% quarter-over-quarter to $3.69B.

Based on UBS O'Connor's 13F filing for Q2 2025, filed 14 Aug 2025.