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Spero Therapeutics
SPRO

Overview Fund Activity

89 hedge funds and large institutions have $370M invested in Spero Therapeutics in 2020 Q4 according to their latest regulatory filings, with 24 funds opening new positions, 34 increasing their positions, 23 reducing their positions, and 13 closing their positions.

Holders
89
Holders Change
+11
Holders Change %
+14.1%
% of All Funds
1.58%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.05%
New
24
Increased
34
Reduced
23
Closed
13
Calls
$1.5M
Puts
$2.04M
Net Calls
-$539K
Net Calls Change
-$142K

Top Buyers

1
AVAX
1
Atlas Venture Associates XI
Massachusetts
$26.7M
2
BI
2
BVF Inc
California
$43.5M
3
BlackRock
3
BlackRock
New York
$33.6M
4
Ameriprise
4
Ameriprise
Minnesota
$5.15M
5
Morgan Stanley
5
Morgan Stanley
New York
$5.26M

Top Sellers

1
ACM
1
Aquilo Capital Management
California
$76.2M
2
NHAS
2
Novo Holdings A/S
Denmark
$11.2M
3
AI
3
Alphabet Inc
California
$17.3M
4
AIC
4
AWM Investment Company
New York
$7.23M
5
AG
5
Artal Group
Luxembourg
$9.7M
Name Market Value Shares Shares
Change 		Shares
Change %
TRCT
76
Tower Research Capital (TRC)
New York
$22K 1,160 -14,624 -93%
Royal Bank of Canada
77
Royal Bank of Canada
Ontario, Canada
$22K 1,137 +510 +81%
CFB
78
Cullen/Frost Bankers
Texas
$19K 1,000 +1,000 New
Nisa Investment Advisors
79
Nisa Investment Advisors
Missouri
$15K 750 +750 New
PCM
80
Penserra Capital Management
California
$12K 625 +625 New
BDWM
81
Brewin Dolphin Wealth Management
Ireland
$11.6K 600 – –
Simplex Trading
82
Simplex Trading
Illinois
$11K 606 +606 New
RE
83
RBC Europe
United Kingdom
$9.27K 478 – –
CG
84
Cutler Group
California
$6K 340 +340 New
IRC
85
Investors Research Corp
Georgia
$1K 75 +45 +150%
Daiwa Securities Group
86
Daiwa Securities Group
Japan
$1K 51 +51 New
AIG
87
American International Group
New York
$230 11,885 +3,045 +34%
ACA
88
Atlas Capital Advisors
Wyoming
$19 1 +1 New
SB
89
Samsara BioCapital
California
– – -160,000 Closed
Renaissance Technologies
90
Renaissance Technologies
New York
– – -153,203 Closed
Jacobs Levy Equity Management
91
Jacobs Levy Equity Management
New Jersey
– – -123,688 Closed
DCM
92
DAFNA Capital Management
California
– – -100,000 Closed
MAM
93
Martingale Asset Management
Massachusetts
– – -43,908 Closed
Arrowstreet Capital
94
Arrowstreet Capital
Massachusetts
– – -34,225 Closed
TI
95
Trexquant Investment
Connecticut
– – -17,975 Closed
Squarepoint
96
Squarepoint
New York
– – -14,690 Closed
VOYA Investment Management
97
VOYA Investment Management
Georgia
– – -14,646 Closed
IWM
98
IHT Wealth Management
Illinois
– – -10,090 Closed
SO
99
STRS Ohio
Ohio
– – -7,100 Closed
Group One Trading
100
Group One Trading
Illinois
– – -4,548 Closed
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4
5