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Spero Therapeutics
SPRO

Overview Fund Activity

94 hedge funds and large institutions have $273M invested in Spero Therapeutics in 2021 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 27 increasing their positions, 26 reducing their positions, and 8 closing their positions.

Holders
94
Holders Change
+5
Holders Change %
+5.62%
% of All Funds
1.66%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.04%
New
15
Increased
27
Reduced
26
Closed
8
Calls
$889K
Puts
$1.58M
Net Calls
-$690K
Net Calls Change
-$151K

Top Buyers

1
State Street
1
State Street
Massachusetts
$20M
2
Goldman Sachs
2
Goldman Sachs
New York
$3.77M
3
Ameriprise
3
Ameriprise
Minnesota
$6.4M
4
Dimensional Fund Advisors
4
Dimensional Fund Advisors
Texas
$5.04M
5
Citigroup
5
Citigroup
New York
$1.27M

Top Sellers

1
RSCM
1
Rock Springs Capital Management
Maryland
$14.2M
2
NHAS
2
Novo Holdings A/S
Denmark
$6.9M
3
BI
3
BVF Inc
California
$31.5M
4
CCM
4
CAAS Capital Management
New York
$0
5
ACM
5
Aquilo Capital Management
California
$56.4M
Name Market Value Shares Shares
Change 		Shares
Change %
ACM
1
Aquilo Capital Management
California
$56.4M 3,829,209 -103,000 -3%
BI
2
BVF Inc
California
$31.5M 2,137,978 -105,300 -5%
BlackRock
3
BlackRock
New York
$26.2M 1,776,596 +44,996 +3%
AVAI
4
Atlas Venture Associates IX
Massachusetts
$20.3M 1,376,968 – –
State Street
5
State Street
Massachusetts
$20M 1,356,543 +1,017,712 +300%
Vanguard Group
6
Vanguard Group
Pennsylvania
$16.3M 1,106,696 -24,034 -2%
RSCM
7
Rock Springs Capital Management
Maryland
$14.2M 965,928 -269,072 -22%
AI
8
Alphabet Inc
California
$13.1M 889,979 – –
AG
9
Artal Group
Luxembourg
$7.36M 500,000 – –
NHAS
10
Novo Holdings A/S
Denmark
$6.9M 468,902 -107,800 -19%
Ameriprise
11
Ameriprise
Minnesota
$6.4M 434,788 +169,347 +64%
AIC
12
AWM Investment Company
New York
$5.49M 372,755 – –
Geode Capital Management
13
Geode Capital Management
Massachusetts
$5.35M 363,611 +5,463 +2%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$5.04M 342,506 +92,309 +37%
GIM
15
Granahan Investment Management
Massachusetts
$5.04M 342,113 -78,207 -19%
Goldman Sachs
16
Goldman Sachs
New York
$3.77M 255,800 +214,179 +515%
Northern Trust
17
Northern Trust
Illinois
$3.53M 239,578 -26,395 -10%
Morgan Stanley
18
Morgan Stanley
New York
$2.78M 188,949 -82,309 -30%
Assenagon Asset Management
19
Assenagon Asset Management
Luxembourg
$2.67M 181,578 +57,793 +47%
Citigroup
20
Citigroup
New York
$1.27M 85,948 +80,845 +1,584%
LBA
21
Letko, Brosseau & Associates
Quebec, Canada
$1.08M 73,659 +5,559 +8%
Susquehanna International Group
22
Susquehanna International Group
Pennsylvania
$1.02M 69,183 -4,895 -7%
Rafferty Asset Management
23
Rafferty Asset Management
New York
$1.02M 68,963 +68,963 New
JPMorgan Chase & Co
24
JPMorgan Chase & Co
New York
$1.01M 68,569 -5,106 -7%
Nuveen Asset Management
25
Nuveen Asset Management
Illinois
$948K 64,350 -18,596 -22%
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