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Spero Therapeutics
SPRO

Overview Fund Activity

48 hedge funds and large institutions have $20.6M invested in Spero Therapeutics in 2023 Q1 according to their latest regulatory filings, with 3 funds opening new positions, 15 increasing their positions, 7 reducing their positions, and 13 closing their positions.

Holders
48
Holders Change
-12
Holders Change %
-20%
% of All Funds
0.77%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
3
Increased
15
Reduced
7
Closed
13
Calls
$30K
Puts
$145K
Net Calls
-$115K
Net Calls Change
-$271K

Top Buyers

1
Vanguard Group
1
Vanguard Group
Pennsylvania
$2.07M
2
AFM
2
Anson Funds Management
Texas
$4.85M
3
BCM
3
Bridgeway Capital Management
Texas
$159K
4
Group One Trading
4
Group One Trading
Illinois
$126K
5
Geode Capital Management
5
Geode Capital Management
Massachusetts
$490K

Top Sellers

1
Millennium Management
1
Millennium Management
New York
$717K
2
OMC
2
Oasis Management Company
Cayman Islands
$0
3
XT
3
XTX Topco
Cayman Islands
$174K
4
TRCT
4
Tower Research Capital (TRC)
New York
$1K
5
VF
5
Virtu Financial
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
AFM
1
Anson Funds Management
Texas
$4.85M 3,344,862 +325,254 +11%
Vanguard Group
2
Vanguard Group
Pennsylvania
$2.07M 1,426,571 +372,183 +35%
AVAI
3
Atlas Venture Associates IX
Massachusetts
$2M 1,376,968 – –
AIC
4
AWM Investment Company
New York
$1.89M 1,300,400 – –
AVLSA
5
Atlas Venture Life Science Advisors
Massachusetts
$1.5M 1,031,160 – –
AI
6
Alphabet Inc
California
$1.29M 889,979 – –
M
7
Murchinson
Ontario, Canada
$1.11M 805,621 +42,921 +6%
RSCM
8
Rock Springs Capital Management
Maryland
$971K 669,533 – –
Millennium Management
9
Millennium Management
New York
$717K 494,541 -381,857 -44%
BlackRock
10
BlackRock
New York
$710K 489,813 +1,730 +0.4%
NHAS
11
Novo Holdings A/S
Denmark
$680K 468,902 – –
Renaissance Technologies
12
Renaissance Technologies
New York
$595K 410,300 +67,400 +20%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$490K 337,856 +80,572 +31%
OMC
14
OUP Management Company
Pennsylvania
$361K 249,070 – –
DCM
15
DAFNA Capital Management
California
$181K 125,000 – –
XT
16
XTX Topco
Cayman Islands
$174K 119,861 -226,873 -65%
State Street
17
State Street
Massachusetts
$161K 110,711 – –
BCM
18
Bridgeway Capital Management
Texas
$159K 109,800 +109,800 New
Group One Trading
19
Group One Trading
Illinois
$126K 87,104 +81,363 +1,417%
Northern Trust
20
Northern Trust
Illinois
$125K 86,256 +16,672 +24%
Marshall Wace
21
Marshall Wace
United Kingdom
$93.4K 64,388 +13,471 +26%
UBS Group
22
UBS Group
Switzerland
$60.2K 41,523 -4,159 -9%
Two Sigma Investments
23
Two Sigma Investments
New York
$46.5K 32,100 -7,695 -19%
Charles Schwab
24
Charles Schwab
California
$41.4K 28,565 – –
Susquehanna International Group
25
Susquehanna International Group
Pennsylvania
$38.5K 26,544 -24,105 -48%
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