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Spero Therapeutics
SPRO

Overview Fund Activity

59 hedge funds and large institutions have $110M invested in Spero Therapeutics in 2019 Q3 according to their latest regulatory filings, with 6 funds opening new positions, 27 increasing their positions, 12 reducing their positions, and 8 closing their positions.

Holders
59
Holders Change
-2
Holders Change %
-3.28%
% of All Funds
1.3%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.09%
New
6
Increased
27
Reduced
12
Closed
8
Calls
–
Puts
$1K
Net Calls
-$1K
Net Calls Change
–

Top Buyers

1
Vanguard Group
1
Vanguard Group
Pennsylvania
$5.27M
2
PAM
2
Panagora Asset Management
Massachusetts
$538K
3
Renaissance Technologies
3
Renaissance Technologies
New York
$2.68M
4
State Street
4
State Street
Massachusetts
$2.09M
5
Northern Trust
5
Northern Trust
Illinois
$1.27M

Top Sellers

1
O
1
OrbiMed
New York
$1.49M
2
FI
2
Fosun International
China
$0
3
Fidelity Investments
3
Fidelity Investments
Massachusetts
$1.81M
4
DCM
4
DAFNA Capital Management
California
$418K
5
Marshall Wace
5
Marshall Wace
United Kingdom
$0
Name Market Value Shares Shares
Change 		Shares
Change %
AVAI
1
Atlas Venture Associates IX
Massachusetts
$14.6M 1,376,968 – –
ACM
2
Aquilo Capital Management
California
$12.2M 1,154,356 – –
AI
3
Alphabet Inc
California
$11.8M 1,112,473 – –
BI
4
BVF Inc
California
$9.96M 939,704 – –
BlackRock
5
BlackRock
New York
$7.2M 678,949 +22,171 +3%
AIC
6
AWM Investment Company
New York
$6.34M 598,315 – –
AG
7
Artal Group
Luxembourg
$5.72M 540,000 – –
RSCM
8
Rock Springs Capital Management
Maryland
$5.57M 525,000 – –
Vanguard Group
9
Vanguard Group
Pennsylvania
$5.27M 496,687 +59,483 +14%
VMI
10
VHCP Management II
New York
$5.03M 474,015 – –
NHAS
11
Novo Holdings A/S
Denmark
$4.94M 465,983 – –
Renaissance Technologies
12
Renaissance Technologies
New York
$2.68M 252,803 +37,900 +18%
State Street
13
State Street
Massachusetts
$2.09M 197,226 +27,695 +16%
Fidelity Investments
14
Fidelity Investments
Massachusetts
$1.81M 170,588 -58,364 -25%
JPMorgan Chase & Co
15
JPMorgan Chase & Co
New York
$1.77M 166,726 +2,337 +1%
GIM
16
Granahan Investment Management
Massachusetts
$1.56M 147,543 +9,248 +7%
O
17
OrbiMed
New York
$1.49M 140,709 -366,762 -72%
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$1.3M 123,005 +16,602 +16%
Northern Trust
19
Northern Trust
Illinois
$1.27M 120,084 +26,334 +28%
Geode Capital Management
20
Geode Capital Management
Massachusetts
$1.24M 116,782 +2,065 +2%
OAM
21
Oxford Asset Management
United Kingdom
$793K 74,808 -4,285 -5%
BCM
22
Bridgeway Capital Management
Texas
$579K 54,579 – –
PAM
23
Panagora Asset Management
Massachusetts
$538K 50,746 +50,583 +31,033%
Nuveen Asset Management
24
Nuveen Asset Management
Illinois
$465K 43,892 +6,416 +17%
DCM
25
DAFNA Capital Management
California
$418K 39,395 -30,605 -44%
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