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Spero Therapeutics

47 hedge funds and large institutions have $21.3M invested in Spero Therapeutics in 2025 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 12 increasing their positions, 6 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more ownership

Funds ownership:

34% less capital invested

Capital invested by funds: $32.1M → $21.3M (-$10.9M)

45% less call options, than puts

Call options by funds: $195K | Put options by funds: $355K

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
47
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$195K
Puts
$355K
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
1
$4.44M
2
$3.74M
3
$3.01M
4
$2.73M
5
$1.67M
6
$992K
7
$817K
8
$531K
9
$392K
10
$359K
11
$283K
12
$244K
13
$217K
14
$216K
15
$207K
16
$201K
17
$120K
18
$92.9K
19
$81.5K
20
$80.8K
21
$76.8K
22
$75.6K
23
$69.5K
24
$63.5K
25
$61.2K