SPRO icon

Spero Therapeutics
SPRO

Overview Fund Activity

50 hedge funds and large institutions have $16.1M invested in Spero Therapeutics in 2024 Q4 according to their latest regulatory filings, with 12 funds opening new positions, 13 increasing their positions, 9 reducing their positions, and 8 closing their positions.

Holders
50
Holders Change
+4
Holders Change %
+8.7%
% of All Funds
0.67%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
12
Increased
13
Reduced
9
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
P
1
Pfizer
New York
$2.43M
2
M
2
Murchinson
Ontario, Canada
$900K
3
MCM
3
Monimus Capital Management
New Jersey
$320K
4
Mackenzie Financial
4
Mackenzie Financial
Ontario, Canada
$193K
5
Renaissance Technologies
5
Renaissance Technologies
New York
$1.14M

Top Sellers

1
NHAS
1
Novo Holdings A/S
Denmark
$0
2
AIC
2
AWM Investment Company
New York
$0
3
AVLSA
3
Atlas Venture Life Science Advisors
Massachusetts
$314K
4
Man Group
4
Man Group
United Kingdom
$0
5
Millennium Management
5
Millennium Management
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
AFM
1
Anson Funds Management
Texas
$3.96M 3,839,886 +89,436 +2%
P
2
Pfizer
New York
$2.43M 2,362,348 +2,362,348 New
Vanguard Group
3
Vanguard Group
Pennsylvania
$1.82M 1,763,620 – –
Renaissance Technologies
4
Renaissance Technologies
New York
$1.14M 1,105,591 +130,938 +13%
Acadian Asset Management
5
Acadian Asset Management
Massachusetts
$1.07M 1,039,922 -31,938 -3%
AI
6
Alphabet Inc
California
$917K 889,979 – –
M
7
Murchinson
Ontario, Canada
$900K 873,910 +873,910 New
ACM
8
ADAR1 Capital Management
Texas
$825K 801,277 +57,818 +8%
BlackRock
9
BlackRock
New York
$500K 485,352 +532 +0.1%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$496K 481,128 -59 -0%
MCM
11
Monimus Capital Management
New Jersey
$320K 310,908 +310,908 New
AVLSA
12
Atlas Venture Life Science Advisors
Massachusetts
$314K 305,255 -97,630 -24%
Mackenzie Financial
13
Mackenzie Financial
Ontario, Canada
$193K 187,559 +155,656 +488%
BCM
14
Bridgeway Capital Management
Texas
$190K 184,800 – –
Citadel Advisors
15
Citadel Advisors
Florida
$178K 172,872 +91,447 +112%
State Street
16
State Street
Massachusetts
$153K 148,911 +18,400 +14%
DCM
17
DAFNA Capital Management
California
$129K 125,000 – –
Northern Trust
18
Northern Trust
Illinois
$89K 86,447 -25,050 -22%
JPMorgan Chase & Co
19
JPMorgan Chase & Co
New York
$63.5K 61,624 +61,388 +26,012%
Squarepoint
20
Squarepoint
New York
$56.7K 55,051 +55,051 New
Jane Street
21
Jane Street
New York
$54.5K 52,869 +52,869 New
Prudential Financial
22
Prudential Financial
New Jersey
$50.7K 49,200 +49,200 New
VF
23
Virtu Financial
New York
$47K 46,046 +46,046 New
XT
24
XTX Topco
Cayman Islands
$31K 30,138 +30,138 New
TSW
25
Three Seasons Wealth
Utah
$30.9K 30,000 – –
1
2 3