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Spero Therapeutics
SPRO

Overview Fund Activity

35 hedge funds and large institutions have $110M invested in Spero Therapeutics in 2018 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 11 increasing their positions, 7 reducing their positions, and 7 closing their positions.

Holders
35
Holders Change
-2
Holders Change %
-5.41%
% of All Funds
0.8%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
5
Increased
11
Reduced
7
Closed
7
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
JPMorgan Chase & Co
1
JPMorgan Chase & Co
New York
$3.65M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$1.58M
3
BCM
3
Bridgeway Capital Management
Texas
$779K
4
State Street
4
State Street
Massachusetts
$451K
5
DCM
5
DAFNA Capital Management
California
$421K

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$10.6M
2
ECM
2
Endurant Capital Management
California
$0
3
LCM
3
Laurion Capital Management
New York
$0
4
DIM
4
DC Investments Management
Virginia
$0
5
TCIM
5
TIAA CREF Investment Management
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
AVAI
1
Atlas Venture Associates IX
Massachusetts
$19.6M 1,376,968 – –
AI
2
Alphabet Inc
California
$15.9M 1,112,473 – –
BI
3
BVF Inc
California
$14.9M 1,048,958 +19,773 +2%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$11.4M 800,000 – –
RCM
5
RA Capital Management
Massachusetts
$10.6M 741,647 -484,000 -39%
RSCM
6
Rock Springs Capital Management
Maryland
$7.48M 525,000 – –
VMI
7
VHCP Management II
New York
$6.92M 485,615 – –
AG
8
Artal Group
Luxembourg
$4.99M 350,000 – –
AIC
9
AWM Investment Company
New York
$4.99M 350,000 – –
JPMorgan Chase & Co
10
JPMorgan Chase & Co
New York
$3.65M 256,353 +255,052 +19,604%
BlackRock
11
BlackRock
New York
$3.6M 252,301 +11,427 +5%
Vanguard Group
12
Vanguard Group
Pennsylvania
$1.58M 111,039 +65,550 +144%
Northern Trust
13
Northern Trust
Illinois
$945K 66,359 +1,234 +2%
BCM
14
Bridgeway Capital Management
Texas
$779K 54,700 +54,700 New
State Street
15
State Street
Massachusetts
$451K 31,673 +31,673 New
DCM
16
DAFNA Capital Management
California
$421K 29,544 +24,544 +491%
California Public Employees Retirement System
17
California Public Employees Retirement System
California
$356K 25,000 – –
Geode Capital Management
18
Geode Capital Management
Massachusetts
$290K 20,396 +20,396 New
Bank of New York Mellon
19
Bank of New York Mellon
New York
$202K 14,199 +14,199 New
Millennium Management
20
Millennium Management
New York
$163K 11,415 +11,415 New
Morgan Stanley
21
Morgan Stanley
New York
$157K 11,030 +477 +5%
California State Teachers Retirement System (CalSTRS)
22
California State Teachers Retirement System (CalSTRS)
California
$136K 9,511 – –
Deutsche Bank
23
Deutsche Bank
Germany
$110K 7,827 -5,466 -41%
AIG
24
American International Group
New York
$55K 3,857 -206 -5%
SO
25
STRS Ohio
Ohio
$24K 1,700 – –
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