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Spero Therapeutics

100 hedge funds and large institutions have $180M invested in Spero Therapeutics in 2022 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 15 increasing their positions, 23 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,360% more call options, than puts

Call options by funds: $219K | Put options by funds: $15K

213% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 8

19% more funds holding

Funds holding: 84100 (+16)

1.4% more ownership

Funds ownership: 61.24%62.63% (+1.4%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

35% less repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 23

43% less capital invested

Capital invested by funds: $316M → $180M (-$137M)

Holders
100
Holders Change
+16
Holders Change %
+19.05%
% of All Funds
1.58%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
25
Increased
15
Reduced
23
Closed
8
Calls
$219K
Puts
$15K
Net Calls
+$204K
Net Calls Change
-$181K
Name Holding Trade Value Shares
Change
Change in
Stake
ACM
1
Aquilo Capital Management
California
$45.9M +$3.25M +317,323 +6%
BlackRock
2
BlackRock
New York
$15.6M -$48.1K -4,696 -0.3%
BI
3
BVF Inc
California
$13.8M
AVAI
4
Atlas Venture Associates IX
Massachusetts
$12M
Vanguard Group
5
Vanguard Group
Pennsylvania
$12M +$231K +22,550 +2%
AVLSA
6
Atlas Venture Life Science Advisors
Massachusetts
$8.97M
RSCM
7
Rock Springs Capital Management
Maryland
$8.62M +$467K +45,600 +5%
AI
8
Alphabet Inc
California
$7.74M
Ameriprise
9
Ameriprise
Minnesota
$5.1M +$2.29M +223,108 +61%
AG
10
Artal Group
Luxembourg
$4.35M
State Street
11
State Street
Massachusetts
$4.33M -$3.55M -346,770 -41%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$4.1M +$143K +14,005 +3%
NHAS
13
Novo Holdings A/S
Denmark
$4.08M
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$3.54M +$366K +35,724 +10%
Osaic Holdings
15
Osaic Holdings
Arizona
$3.47M -$307 -30 -3%
AIC
16
AWM Investment Company
New York
$3.24M
OMC
17
OUP Management Company
Pennsylvania
$2.17M
Northern Trust
18
Northern Trust
Illinois
$2.07M -$151K -14,748 -6%
Royal Bank of Canada
19
Royal Bank of Canada
Ontario, Canada
$1.71M +$138K +13,502 +7%
Goldman Sachs
20
Goldman Sachs
New York
$1.23M +$28.8K +2,815 +2%
GIM
21
Granahan Investment Management
Massachusetts
$986K -$2.72M -265,610 -70%
Renaissance Technologies
22
Renaissance Technologies
New York
$949K +$1.12M +109,100 New
JP Morgan Chase
23
JP Morgan Chase
New York
$706K -$164K -16,013 -16%
Two Sigma Investments
24
Two Sigma Investments
New York
$686K +$808K +78,908 New
LBA
25
Letko, Brosseau & Associates
Quebec, Canada
$641K

SPRO Hedge Fund Activity: Q1 2022 in Review

100 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Spero Therapeutics (SPRO) for Q1 2022, worth a combined $180M — down 43% from $316M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new SPRO positions and 8 closed out — a net gain of 17 holders — while 15 added to existing stakes and 23 trimmed.

The largest buyer was Aquilo Capital Management, adding an estimated $3.25M. The largest seller was State Street, cutting an estimated $3.55M.

  • 100 institutional investors held Spero Therapeutics (SPRO) as of Q1 2022, up from 84 in Q4 2021.
  • Funds reported $180M of Spero Therapeutics stock for Q1 2022, down 43% quarter-over-quarter.
  • 25 funds opened new Spero Therapeutics positions in Q1 2022 and 8 closed out, a net change of +17 holders.
  • The largest Spero Therapeutics buyer in Q1 2022 was Aquilo Capital Management, an estimated $3.25M added.
  • The largest Spero Therapeutics seller in Q1 2022 was State Street, an estimated $3.55M sold.

Based on aggregated 13F filings for Q1 2022.