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Spero Therapeutics
SPRO

Overview Fund Activity

53 hedge funds and large institutions have $113M invested in Spero Therapeutics in 2018 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 24 increasing their positions, 6 reducing their positions, and 5 closing their positions.

Holders
53
Holders Change
+9
Holders Change %
+20.45%
% of All Funds
1.21%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
14
Increased
24
Reduced
6
Closed
5
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
EC
1
EcoR1 Capital
California
$9.38M
2
BI
2
BVF Inc
California
$15.6M
3
AIC
3
AWM Investment Company
New York
$5.68M
4
ACM
4
Aquilo Capital Management
California
$8.41M
5
Vanguard Group
5
Vanguard Group
Pennsylvania
$4.79M

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$0
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$6.5M
3
Jacobs Levy Equity Management
3
Jacobs Levy Equity Management
New Jersey
$174K
4
Acadian Asset Management
4
Acadian Asset Management
Massachusetts
$0
5
SO
5
STRS Ohio
Ohio
$0
Name Market Value Shares Shares
Change 		Shares
Change %
BI
1
BVF Inc
California
$15.6M 1,488,088 +439,130 +42%
AVAI
2
Atlas Venture Associates IX
Massachusetts
$14.5M 1,376,968 – –
AI
3
Alphabet Inc
California
$11.7M 1,112,473 – –
EC
4
EcoR1 Capital
California
$9.38M 892,741 +892,741 New
ACM
5
Aquilo Capital Management
California
$8.41M 799,691 +383,000 +92%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$6.5M 618,206 -181,794 -23%
AG
7
Artal Group
Luxembourg
$6.31M 600,000 +250,000 +71%
AIC
8
AWM Investment Company
New York
$5.68M 540,474 +400,000 +285%
RSCM
9
Rock Springs Capital Management
Maryland
$5.52M 525,000 – –
VMI
10
VHCP Management II
New York
$4.98M 474,015 – –
Vanguard Group
11
Vanguard Group
Pennsylvania
$4.79M 455,416 +330,580 +265%
BlackRock
12
BlackRock
New York
$3.92M 372,469 +30,470 +9%
SCM
13
Stonepine Capital Management
Oregon
$2.38M 226,444 +226,444 New
JPMorgan Chase & Co
14
JPMorgan Chase & Co
New York
$1.86M 176,483 +37,840 +27%
UOC
15
UBS O'Connor
Illinois
$1.79M 170,000 +170,000 New
GIM
16
Granahan Investment Management
Massachusetts
$1.65M 157,058 +5,910 +4%
State Street
17
State Street
Massachusetts
$1.34M 127,925 +66,727 +109%
Northern Trust
18
Northern Trust
Illinois
$1.01M 95,795 +29,145 +44%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$924K 87,966 +34,476 +64%
BCM
20
Bridgeway Capital Management
Texas
$826K 78,579 +23,879 +44%
DCM
21
DAFNA Capital Management
California
$736K 70,000 +70,000 New
SSA
22
Schonfeld Strategic Advisors
New York
$526K 50,000 +50,000 New
Point72 Asset Management
23
Point72 Asset Management
Connecticut
$462K 44,000 +44,000 New
Bank of New York Mellon
24
Bank of New York Mellon
New York
$293K 27,828 +3,139 +13%
HCMT
25
Highland Capital Management (Texas)
Texas
$210K 20,000 +20,000 New
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