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Spero Therapeutics
SPRO

Overview Fund Activity

60 hedge funds and large institutions have $24.6M invested in Spero Therapeutics in 2022 Q4 according to their latest regulatory filings, with 14 funds opening new positions, 11 increasing their positions, 17 reducing their positions, and 23 closing their positions.

Holders
60
Holders Change
-9
Holders Change %
-13.04%
% of All Funds
0.97%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
14
Increased
11
Reduced
17
Closed
23
Calls
$382K
Puts
$226K
Net Calls
+$156K
Net Calls Change
+$419K

Top Buyers

1
AFM
1
Anson Funds Management
Texas
$5.22M
2
XT
2
XTX Topco
Cayman Islands
$600K
3
Millennium Management
3
Millennium Management
New York
$1.52M
4
Renaissance Technologies
4
Renaissance Technologies
New York
$593K
5
Two Sigma Investments
5
Two Sigma Investments
New York
$68.8K

Top Sellers

1
ACM
1
Aquilo Capital Management
California
$0
2
BI
2
BVF Inc
California
$0
3
AIC
3
AWM Investment Company
New York
$2.25M
4
AG
4
Artal Group
Luxembourg
$0
5
AQR Capital Management
5
AQR Capital Management
Connecticut
$0
Name Market Value Shares Shares
Change 		Shares
Change %
AFM
1
Anson Funds Management
Texas
$5.22M 3,019,608 +1,545,736 +105%
AVAI
2
Atlas Venture Associates IX
Massachusetts
$2.38M 1,376,968 – –
AIC
3
AWM Investment Company
New York
$2.25M 1,300,400 -1,000,000 -43%
Vanguard Group
4
Vanguard Group
Pennsylvania
$1.82M 1,054,388 +665 +0.1%
AVLSA
5
Atlas Venture Life Science Advisors
Massachusetts
$1.78M 1,031,160 – –
AI
6
Alphabet Inc
California
$1.54M 889,979 – –
Millennium Management
7
Millennium Management
New York
$1.52M 876,398 +188,002 +27%
M
8
Murchinson
Ontario, Canada
$1.32M 762,700 – –
RSCM
9
Rock Springs Capital Management
Maryland
$1.16M 669,533 -101,177 -13%
BlackRock
10
BlackRock
New York
$844K 488,083 -204,055 -29%
NHAS
11
Novo Holdings A/S
Denmark
$811K 468,902 – –
XT
12
XTX Topco
Cayman Islands
$600K 346,734 +346,734 New
Renaissance Technologies
13
Renaissance Technologies
New York
$593K 342,900 +128,200 +60%
OMC
14
Oasis Management Company
Cayman Islands
$498K 288,000 – –
Geode Capital Management
15
Geode Capital Management
Massachusetts
$445K 257,284 -32,974 -11%
OMC
16
OUP Management Company
Pennsylvania
$431K 249,070 – –
DCM
17
DAFNA Capital Management
California
$216K 125,000 – –
State Street
18
State Street
Massachusetts
$192K 110,711 +19,400 +21%
Northern Trust
19
Northern Trust
Illinois
$120K 69,584 -379 -0.5%
Marshall Wace
20
Marshall Wace
United Kingdom
$88.1K 50,917 -135,653 -73%
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$87.6K 50,649 -18,637 -27%
UBS Group
22
UBS Group
Switzerland
$79K 45,682 +22,774 +99%
Two Sigma Investments
23
Two Sigma Investments
New York
$68.8K 39,795 +39,795 New
VF
24
Virtu Financial
New York
$59K 34,369 +34,369 New
TRCT
25
Tower Research Capital (TRC)
New York
$57K 33,164 +14,925 +82%
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