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Spero Therapeutics

60 hedge funds and large institutions have $24.6M invested in Spero Therapeutics in 2022 Q4 according to their latest regulatory filings, with 14 funds opening new positions, 11 increasing their positions, 17 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

69% more call options, than puts

Call options by funds: $382K | Put options by funds: $226K

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

13% less funds holding

Funds holding: 6960 (-9)

29.14% less ownership

Funds ownership: 56.61%27.47% (-29%)

35% less repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 17

37% less capital invested

Capital invested by funds: $39.3M → $24.6M (-$14.7M)

39% less first-time investments, than exits

New positions opened: 14 | Existing positions closed: 23

Holders
60
Holders Change
-9
Holders Change %
-13.04%
% of All Funds
0.96%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
14
Increased
11
Reduced
17
Closed
23
Calls
$382K
Puts
$226K
Net Calls
+$156K
Net Calls Change
+$419K
Name Holding Trade Value Shares
Change
Change in
Stake
AFM
1
Anson Funds Management
Texas
$5.22M +$2.89M +1,545,736 +105%
AVAI
2
Atlas Venture Associates IX
Massachusetts
$2.38M
AIC
3
AWM Investment Company
New York
$2.25M -$1.87M -1,000,000 -43%
Vanguard Group
4
Vanguard Group
Pennsylvania
$1.82M +$1.24K +665 +0.1%
AVLSA
5
Atlas Venture Life Science Advisors
Massachusetts
$1.78M
AI
6
Alphabet Inc
California
$1.54M
Millennium Management
7
Millennium Management
New York
$1.52M +$351K +188,002 +27%
M
8
Murchinson
Ontario, Canada
$1.32M
RSCM
9
Rock Springs Capital Management
Maryland
$1.16M -$189K -101,177 -13%
BlackRock
10
BlackRock
New York
$844K -$381K -204,055 -29%
NHAS
11
Novo Holdings A/S
Denmark
$811K
XT
12
XTX Topco
Cayman Islands
$600K +$647K +346,734 New
Renaissance Technologies
13
Renaissance Technologies
New York
$593K +$239K +128,200 +60%
OMC
14
Oasis Management Company
Cayman Islands
$498K
Geode Capital Management
15
Geode Capital Management
Massachusetts
$445K -$61.6K -32,974 -11%
OMC
16
OUP Management Company
Pennsylvania
$431K
DCM
17
DAFNA Capital Management
California
$216K
State Street
18
State Street
Massachusetts
$192K +$36.2K +19,400 +21%
Northern Trust
19
Northern Trust
Illinois
$120K -$708 -379 -0.5%
Marshall Wace
20
Marshall Wace
United Kingdom
$88.1K -$253K -135,653 -73%
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$87.6K -$34.8K -18,637 -27%
UBS Group
22
UBS Group
Switzerland
$79K +$42.5K +22,774 +99%
Two Sigma Investments
23
Two Sigma Investments
New York
$68.8K +$74.3K +39,795 New
VF
24
Virtu Financial
New York
$59K +$64.2K +34,369 New
TRCT
25
Tower Research Capital (TRC)
New York
$57K +$27.9K +14,925 +82%

SPRO Hedge Fund Activity: Q4 2022 in Review

60 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Spero Therapeutics (SPRO) for Q4 2022, worth a combined $24.6M — down 37% from $39.3M a quarter earlier.

Sellers outnumbered buyers: 23 funds closed out of SPRO and 14 opened new positions — a net loss of 9 holders — while 17 trimmed existing stakes and 11 added.

The largest buyer was Anson Funds Management, adding an estimated $2.89M. The largest seller was Aquilo Capital Management, exiting entirely with an estimated $6.81M sold.

  • 60 institutional investors held Spero Therapeutics (SPRO) as of Q4 2022, down from 69 in Q3 2022.
  • Funds reported $24.6M of Spero Therapeutics stock for Q4 2022, down 37% quarter-over-quarter.
  • 14 funds opened new Spero Therapeutics positions in Q4 2022 and 23 closed out, a net change of -9 holders.
  • The largest Spero Therapeutics buyer in Q4 2022 was Anson Funds Management, an estimated $2.89M added.
  • The largest Spero Therapeutics seller in Q4 2022 was Aquilo Capital Management, an estimated $6.81M sold.

Based on aggregated 13F filings for Q4 2022.