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Spero Therapeutics

52 hedge funds and large institutions have $56M invested in Spero Therapeutics in 2018 Q4 according to their latest regulatory filings, with 9 funds opening new positions, 17 increasing their positions, 14 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

21% more repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 14

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

2% less funds holding

Funds holding: 5352 (-1)

6.29% less ownership

Funds ownership: 59.16%52.87% (-6.3%)

10% less first-time investments, than exits

New positions opened: 9 | Existing positions closed: 10

50% less capital invested

Capital invested by funds: $113M → $56M (-$57M)

Holders
52
Holders Change
-1
Holders Change %
-1.89%
% of All Funds
1.16%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
9
Increased
17
Reduced
14
Closed
10
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
AVAI
1
Atlas Venture Associates IX
Massachusetts
$8.47M
AI
2
Alphabet Inc
California
$6.84M
ACM
3
Aquilo Capital Management
California
$6.35M +$1.88M +232,256 +29%
BI
4
BVF Inc
California
$5.18M -$5.22M -644,942 -43%
AG
5
Artal Group
Luxembourg
$3.69M
RSCM
6
Rock Springs Capital Management
Maryland
$3.23M
AIC
7
AWM Investment Company
New York
$3.22M -$133K -16,449 -3%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$3M -$1.05M -129,654 -21%
VMI
9
VHCP Management II
New York
$2.92M
BlackRock
10
BlackRock
New York
$2.42M +$171K +21,161 +6%
JP Morgan Chase
11
JP Morgan Chase
New York
$1.15M +$78.5K +9,693 +5%
FI
12
Fosun International
China
$1.04M +$1.31M +162,362 New
UOC
13
UBS O'Connor
Illinois
$1.03M -$16.1K -1,982 -1%
Vanguard Group
14
Vanguard Group
Pennsylvania
$1M -$2.37M -292,852 -64%
GIM
15
Granahan Investment Management
Massachusetts
$949K -$22.3K -2,752 -2%
State Street
16
State Street
Massachusetts
$935K +$196K +24,168 +19%
Northern Trust
17
Northern Trust
Illinois
$595K +$8.41K +1,038 +1%
Geode Capital Management
18
Geode Capital Management
Massachusetts
$564K +$31.4K +3,876 +4%
Bank of America
19
Bank of America
North Carolina
$510K +$641K +79,123 +2,036%
DCM
20
DAFNA Capital Management
California
$431K
OAM
21
Oxford Asset Management
United Kingdom
$298K +$281K +34,666 +253%
Renaissance Technologies
22
Renaissance Technologies
New York
$264K +$250K +30,903 +258%
Bank of New York Mellon
23
Bank of New York Mellon
New York
$226K +$72K +8,888 +32%
BCM
24
Bridgeway Capital Management
Texas
$176K -$405K -50,000 -64%
Two Sigma Investments
25
Two Sigma Investments
New York
$169K +$222K +27,454 New

SPRO Hedge Fund Activity: Q4 2018 in Review

52 of the 4,488 institutional investors tracked by Wall St. Rank reported a position in Spero Therapeutics (SPRO) for Q4 2018, worth a combined $56M — down 50% from $113M a quarter earlier.

Sellers outnumbered buyers: 10 funds closed out of SPRO and 9 opened new positions — a net loss of 1 holder — while 14 trimmed existing stakes and 17 added.

The largest buyer was Aquilo Capital Management, adding an estimated $1.88M. The largest seller was EcoR1 Capital, exiting entirely with an estimated $9.38M sold.

  • 52 institutional investors held Spero Therapeutics (SPRO) as of Q4 2018, down from 53 in Q3 2018.
  • Funds reported $56M of Spero Therapeutics stock for Q4 2018, down 50% quarter-over-quarter.
  • 9 funds opened new Spero Therapeutics positions in Q4 2018 and 10 closed out, a net change of -1 holder.
  • The largest Spero Therapeutics buyer in Q4 2018 was Aquilo Capital Management, an estimated $1.88M added.
  • The largest Spero Therapeutics seller in Q4 2018 was EcoR1 Capital, an estimated $9.38M sold.

Based on aggregated 13F filings for Q4 2018.