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Spero Therapeutics
SPRO

Overview Fund Activity

61 hedge funds and large institutions have $104M invested in Spero Therapeutics in 2019 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 28 increasing their positions, 11 reducing their positions, and 6 closing their positions.

Holders
61
Holders Change
+2
Holders Change %
+3.39%
% of All Funds
1.2%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.06%
New
8
Increased
28
Reduced
11
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
NHAS
1
Novo Holdings A/S
Denmark
$8.95M
2
Renaissance Technologies
2
Renaissance Technologies
New York
$3.25M
3
BlackRock
3
BlackRock
New York
$7.26M
4
Jacobs Levy Equity Management
4
Jacobs Levy Equity Management
New Jersey
$441K
5
Dimensional Fund Advisors
5
Dimensional Fund Advisors
Texas
$1.5M

Top Sellers

1
AIC
1
AWM Investment Company
New York
$4.56M
2
BI
2
BVF Inc
California
$8.13M
3
Fidelity Investments
3
Fidelity Investments
Massachusetts
$951K
4
DCM
4
DAFNA Capital Management
California
$0
5
AG
5
Artal Group
Luxembourg
$4.81M
Name Market Value Shares Shares
Change 		Shares
Change %
AVAI
1
Atlas Venture Associates IX
Massachusetts
$13.2M 1,376,968 – –
ACM
2
Aquilo Capital Management
California
$11.1M 1,154,356 – –
AI
3
Alphabet Inc
California
$10.7M 1,112,473 – –
NHAS
4
Novo Holdings A/S
Denmark
$8.95M 931,099 +465,116 +100%
BI
5
BVF Inc
California
$8.13M 845,405 -94,299 -10%
BlackRock
6
BlackRock
New York
$7.26M 755,265 +76,316 +11%
RSCM
7
Rock Springs Capital Management
Maryland
$5.05M 525,000 – –
AG
8
Artal Group
Luxembourg
$4.81M 500,000 -40,000 -7%
Vanguard Group
9
Vanguard Group
Pennsylvania
$4.77M 496,401 -286 -0.1%
AIC
10
AWM Investment Company
New York
$4.56M 474,344 -123,971 -21%
VMI
11
VHCP Management II
New York
$4.56M 474,015 – –
Renaissance Technologies
12
Renaissance Technologies
New York
$3.25M 338,203 +85,400 +34%
State Street
13
State Street
Massachusetts
$2.01M 208,591 +11,365 +6%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$1.5M 155,480 +32,475 +26%
GIM
15
Granahan Investment Management
Massachusetts
$1.43M 148,867 +1,324 +0.9%
Northern Trust
16
Northern Trust
Illinois
$1.31M 135,997 +15,913 +13%
JPMorgan Chase & Co
17
JPMorgan Chase & Co
New York
$1.28M 133,278 -33,448 -20%
O
18
OrbiMed
New York
$1.27M 131,653 -9,056 -6%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$1.15M 119,452 +2,670 +2%
Fidelity Investments
20
Fidelity Investments
Massachusetts
$951K 98,952 -71,636 -42%
BCM
21
Bridgeway Capital Management
Texas
$679K 70,579 +16,000 +29%
OAM
22
Oxford Asset Management
United Kingdom
$566K 58,868 -15,940 -21%
Jacobs Levy Equity Management
23
Jacobs Levy Equity Management
New Jersey
$441K 45,853 +35,788 +356%
PAM
24
Panagora Asset Management
Massachusetts
$394K 41,033 -9,713 -19%
Nuveen Asset Management
25
Nuveen Asset Management
Illinois
$369K 38,397 -5,495 -13%
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