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Spero Therapeutics
SPRO

Overview Fund Activity

87 hedge funds and large institutions have $338M invested in Spero Therapeutics in 2021 Q3 according to their latest regulatory filings, with 6 funds opening new positions, 22 increasing their positions, 25 reducing their positions, and 7 closing their positions.

Holders
87
Holders Change
-1
Holders Change %
-1.14%
% of All Funds
1.53%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
6
Increased
22
Reduced
25
Closed
7
Calls
$2.01M
Puts
$1.21M
Net Calls
+$795K
Net Calls Change
+$197K

Top Buyers

1
ACM
1
Aquilo Capital Management
California
$84M
2
GIM
2
Granahan Investment Management
Massachusetts
$10.2M
3
Royal Bank of Canada
3
Royal Bank of Canada
Ontario, Canada
$3.32M
4
WJWM
4
Williams Jones Wealth Management
New York
$1.94M
5
BGIM
5
Brandywine Global Investment Management
Pennsylvania
$1.08M

Top Sellers

1
BI
1
BVF Inc
California
$33.3M
2
Ameriprise
2
Ameriprise
Minnesota
$6.94M
3
Dimensional Fund Advisors
3
Dimensional Fund Advisors
Texas
$6.07M
4
Wells Fargo
4
Wells Fargo
California
$144K
5
RSCM
5
Rock Springs Capital Management
Maryland
$17.3M
Name Market Value Shares Shares
Change 		Shares
Change %
ACM
1
Aquilo Capital Management
California
$84M 4,563,688 +734,479 +19%
BI
2
BVF Inc
California
$33.3M 1,809,352 -328,626 -15%
BlackRock
3
BlackRock
New York
$33.2M 1,802,528 +23,706 +1%
AVAI
4
Atlas Venture Associates IX
Massachusetts
$25.4M 1,376,968 – –
Vanguard Group
5
Vanguard Group
Pennsylvania
$23.8M 1,292,498 +15,708 +1%
RSCM
6
Rock Springs Capital Management
Maryland
$17.3M 941,543 -24,385 -3%
AI
7
Alphabet Inc
California
$16.4M 889,979 – –
State Street
8
State Street
Massachusetts
$14.8M 802,691 -8,047 -1%
GIM
9
Granahan Investment Management
Massachusetts
$10.2M 555,614 +222,975 +67%
AG
10
Artal Group
Luxembourg
$9.21M 500,000 – –
NHAS
11
Novo Holdings A/S
Denmark
$8.63M 468,902 – –
Geode Capital Management
12
Geode Capital Management
Massachusetts
$8.19M 444,914 +31,153 +8%
Ameriprise
13
Ameriprise
Minnesota
$6.94M 377,095 -61,742 -14%
AIC
14
AWM Investment Company
New York
$6.86M 372,755 – –
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$6.07M 329,633 -44,810 -12%
Northern Trust
16
Northern Trust
Illinois
$4.75M 257,939 -2,947 -1%
Royal Bank of Canada
17
Royal Bank of Canada
Ontario, Canada
$3.32M 180,102 +177,945 +8,250%
Goldman Sachs
18
Goldman Sachs
New York
$2.53M 137,579 +1,317 +1%
WJWM
19
Williams Jones Wealth Management
New York
$1.94M 105,500 +105,500 New
JPMorgan Chase & Co
20
JPMorgan Chase & Co
New York
$1.93M 104,934 -10,922 -9%
Bank of New York Mellon
21
Bank of New York Mellon
New York
$1.37M 74,207 +7,612 +11%
Nuveen Asset Management
22
Nuveen Asset Management
Illinois
$1.36M 71,121 +7,079 +11%
LBA
23
Letko, Brosseau & Associates
Quebec, Canada
$1.36M 73,659 – –
New York State Common Retirement Fund
24
New York State Common Retirement Fund
New York
$1.31M 71,220 +21,329 +43%
Charles Schwab
25
Charles Schwab
California
$1.17M 63,586 +3,090 +5%
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