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Spero Therapeutics

89 hedge funds and large institutions have $370M invested in Spero Therapeutics in 2020 Q4 according to their latest regulatory filings, with 24 funds opening new positions, 34 increasing their positions, 23 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

99% more capital invested

Capital invested by funds: $186M → $370M (+$184M)

85% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 13

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

48% more repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 23

14% more funds holding

Funds holding: 7889 (+11)

5.53% more ownership

Funds ownership: 64.67%70.19% (+5.5%)

26% less call options, than puts

Call options by funds: $1.5M | Put options by funds: $2.04M

Holders
89
Holders Change
+11
Holders Change %
+14.1%
% of All Funds
1.57%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.05%
New
24
Increased
34
Reduced
23
Closed
13
Calls
$1.5M
Puts
$2.04M
Net Calls
-$539K
Net Calls Change
-$142K
Name Holding Trade Value Shares
Change
Change in
Stake
ACM
1
Aquilo Capital Management
California
$76.2M -$8.81M -564,933 -13%
BI
2
BVF Inc
California
$43.5M +$14M +898,944 +67%
BlackRock
3
BlackRock
New York
$33.6M +$10.2M +654,438 +61%
AVAI
4
Atlas Venture Associates IX
Massachusetts
$26.7M
AVAX
5
Atlas Venture Associates XI
Massachusetts
$26.7M +$21.5M +1,376,968 New
RSCM
6
Rock Springs Capital Management
Maryland
$23.9M -$19.6K -1,256 -0.1%
Vanguard Group
7
Vanguard Group
Pennsylvania
$21.9M +$3.15M +201,832 +22%
AI
8
Alphabet Inc
California
$17.3M -$3.47M -222,494 -20%
NHAS
9
Novo Holdings A/S
Denmark
$11.2M -$5.52M -354,397 -38%
AG
10
Artal Group
Luxembourg
$9.7M -$1.56M -100,000 -17%
GIM
11
Granahan Investment Management
Massachusetts
$8.15M +$721K +46,242 +12%
AIC
12
AWM Investment Company
New York
$7.23M -$1.96M -126,000 -25%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$6.94M +$2.47M +158,719 +80%
State Street
14
State Street
Massachusetts
$6.57M +$830K +53,239 +19%
Morgan Stanley
15
Morgan Stanley
New York
$5.26M +$3.87M +248,326 +1,083%
Northern Trust
16
Northern Trust
Illinois
$5.16M +$856K +54,896 +26%
Ameriprise
17
Ameriprise
Minnesota
$5.15M +$4.14M +265,441 New
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$4.85M +$299K +19,188 +8%
Assenagon Asset Management
19
Assenagon Asset Management
Luxembourg
$2.4M +$1.93M +123,785 New
N
20
Nuveen
North Carolina
$1.61M +$499K +31,982 +63%
CCM
21
CAAS Capital Management
New York
$1.52M +$1.22M +78,509 New
Susquehanna International Group
22
Susquehanna International Group
Pennsylvania
$1.44M +$260K +16,670 +29%
JP Morgan Chase
23
JP Morgan Chase
New York
$1.43M -$253K -16,213 -18%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$1.35M +$286K +18,357 +36%
LBA
25
Letko, Brosseau & Associates
Quebec, Canada
$1.32M +$1.06M +68,100 New

SPRO Hedge Fund Activity: Q4 2020 in Review

89 of the 5,651 institutional investors tracked by Wall St. Rank reported a position in Spero Therapeutics (SPRO) for Q4 2020, worth a combined $370M — up 99% from $186M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new SPRO positions and 13 closed out — a net gain of 11 holders — while 34 added to existing stakes and 23 trimmed.

The largest buyer was BVF Inc, adding an estimated $14M. The largest seller was Aquilo Capital Management, cutting an estimated $8.81M.

  • 89 institutional investors held Spero Therapeutics (SPRO) as of Q4 2020, up from 78 in Q3 2020.
  • Funds reported $370M of Spero Therapeutics stock for Q4 2020, up 99% quarter-over-quarter.
  • 24 funds opened new Spero Therapeutics positions in Q4 2020 and 13 closed out, a net change of +11 holders.
  • The largest Spero Therapeutics buyer in Q4 2020 was BVF Inc, an estimated $14M added.
  • The largest Spero Therapeutics seller in Q4 2020 was Aquilo Capital Management, an estimated $8.81M sold.

Based on aggregated 13F filings for Q4 2020.