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Spero Therapeutics
SPRO

Overview Fund Activity

54 hedge funds and large institutions have $23.7M invested in Spero Therapeutics in 2024 Q1 according to their latest regulatory filings, with 11 funds opening new positions, 12 increasing their positions, 12 reducing their positions, and 7 closing their positions.

Holders
54
Holders Change
+4
Holders Change %
+8%
% of All Funds
0.78%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
11
Increased
12
Reduced
12
Closed
7
Calls
$60K
Puts
–
Net Calls
+$60K
Net Calls Change
+$89K

Top Buyers

1
Acadian Asset Management
1
Acadian Asset Management
Massachusetts
$1.31M
2
Renaissance Technologies
2
Renaissance Technologies
New York
$1.47M
3
SC
3
Shay Capital
New York
$528K
4
Man Group
4
Man Group
United Kingdom
$368K
5
Bank of Montreal
5
Bank of Montreal
Ontario, Canada
$140K

Top Sellers

1
AFM
1
Anson Funds Management
Texas
$6.45M
2
AVLSA
2
Atlas Venture Life Science Advisors
Massachusetts
$1.05M
3
Ameriprise
3
Ameriprise
Minnesota
$0
4
ACM
4
ADAR1 Capital Management
Texas
$1.59M
5
XT
5
XTX Topco
Cayman Islands
$25.8K
Name Market Value Shares Shares
Change 		Shares
Change %
AFM
1
Anson Funds Management
Texas
$6.45M 3,750,450 -547,249 -13%
Vanguard Group
2
Vanguard Group
Pennsylvania
$2.84M 1,653,432 +9,675 +0.6%
ACM
3
ADAR1 Capital Management
Texas
$1.59M 926,929 -140,782 -13%
AI
4
Alphabet Inc
California
$1.53M 889,979 – –
M
5
Murchinson
Ontario, Canada
$1.5M 873,910 +11,210 +1%
Renaissance Technologies
6
Renaissance Technologies
New York
$1.47M 854,460 +306,995 +56%
Acadian Asset Management
7
Acadian Asset Management
Massachusetts
$1.31M 762,598 +418,742 +122%
AVLSA
8
Atlas Venture Life Science Advisors
Massachusetts
$1.05M 607,613 -405,825 -40%
BlackRock
9
BlackRock
New York
$820K 476,896 -3,703 -0.8%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$808K 469,441 +56,734 +14%
NHAS
11
Novo Holdings A/S
Denmark
$807K 468,902 – –
AIC
12
AWM Investment Company
New York
$573K 333,400 – –
SC
13
Shay Capital
New York
$528K 306,967 +306,967 New
Man Group
14
Man Group
United Kingdom
$368K 214,026 +214,026 New
BCM
15
Bridgeway Capital Management
Texas
$318K 184,800 +50,000 +37%
Millennium Management
16
Millennium Management
New York
$254K 147,872 -985 -0.7%
State Street
17
State Street
Massachusetts
$224K 130,511 – –
DCM
18
DAFNA Capital Management
California
$215K 125,000 – –
Northern Trust
19
Northern Trust
Illinois
$197K 114,559 +25,678 +29%
Bank of Montreal
20
Bank of Montreal
Ontario, Canada
$140K 79,500 +79,500 New
Squarepoint
21
Squarepoint
New York
$137K 79,401 -43,401 -35%
B
22
Bailard
California
$105K 60,900 +60,900 New
DIM
23
DLK Investment Management
California
$53.9K 31,355 – –
Charles Schwab
24
Charles Schwab
California
$49.1K 28,565 – –
GCP
25
GSA Capital Partners
United Kingdom
$49K 28,319 +28,319 New
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