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Spero Therapeutics
SPRO

Overview Fund Activity

78 hedge funds and large institutions have $186M invested in Spero Therapeutics in 2020 Q3 according to their latest regulatory filings, with 13 funds opening new positions, 30 increasing their positions, 22 reducing their positions, and 15 closing their positions.

Holders
78
Holders Change
-2
Holders Change %
-2.5%
% of All Funds
1.58%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
13
Increased
30
Reduced
22
Closed
15
Calls
$217K
Puts
$614K
Net Calls
-$397K
Net Calls Change
-$416K

Top Buyers

1
ACM
1
Aquilo Capital Management
California
$50.2M
2
BI
2
BVF Inc
California
$15M
3
RSCM
3
Rock Springs Capital Management
Maryland
$13.8M
4
AIC
4
AWM Investment Company
New York
$5.57M
5
GIM
5
Granahan Investment Management
Massachusetts
$4.18M

Top Sellers

1
Renaissance Technologies
1
Renaissance Technologies
New York
$1.71M
2
Jacobs Levy Equity Management
2
Jacobs Levy Equity Management
New Jersey
$1.38M
3
Bessemer Group
3
Bessemer Group
New Jersey
$0
4
Two Sigma Investments
4
Two Sigma Investments
New York
$0
5
MAM
5
Martingale Asset Management
Massachusetts
$491K
Name Market Value Shares Shares
Change 		Shares
Change %
ACM
1
Aquilo Capital Management
California
$50.2M 4,497,142 +2,554,061 +131%
AVAI
2
Atlas Venture Associates IX
Massachusetts
$15.4M 1,376,968 – –
BI
3
BVF Inc
California
$15M 1,344,334 +857,794 +176%
RSCM
4
Rock Springs Capital Management
Maryland
$13.8M 1,236,256 +621,079 +101%
AI
5
Alphabet Inc
California
$12.4M 1,112,473 – –
BlackRock
6
BlackRock
New York
$12M 1,077,162 +126,906 +13%
NHAS
7
Novo Holdings A/S
Denmark
$10.4M 931,099 – –
Vanguard Group
8
Vanguard Group
Pennsylvania
$10.4M 928,898 +193,664 +26%
AG
9
Artal Group
Luxembourg
$6.7M 600,000 +54,960 +10%
AIC
10
AWM Investment Company
New York
$5.57M 498,755 +255,000 +105%
GIM
11
Granahan Investment Management
Massachusetts
$4.18M 374,078 +207,472 +125%
State Street
12
State Street
Massachusetts
$3.19M 285,592 -2,982 -1%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$2.58M 231,009 +16,854 +8%
Northern Trust
14
Northern Trust
Illinois
$2.36M 211,077 +1,160 +0.6%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$2.23M 199,429 +2,729 +1%
SB
16
Samsara BioCapital
California
$1.79M 160,000 +160,000 New
Renaissance Technologies
17
Renaissance Technologies
New York
$1.71M 153,203 -176,700 -54%
Jacobs Levy Equity Management
18
Jacobs Levy Equity Management
New Jersey
$1.38M 123,688 -62,662 -34%
Russell Investments Group
19
Russell Investments Group
United Kingdom
$1.29M 116,528 +23,200 +25%
Alyeska Investment Group
20
Alyeska Investment Group
Illinois
$1.12M 100,000 +100,000 New
DCM
21
DAFNA Capital Management
California
$1.12M 100,000 +100,000 New
JPMorgan Chase & Co
22
JPMorgan Chase & Co
New York
$895K 89,888 -9,887 -10%
Susquehanna International Group
23
Susquehanna International Group
Pennsylvania
$641K 57,408 +17,158 +43%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$575K 51,526 +1,589 +3%
Nuveen Asset Management
25
Nuveen Asset Management
Illinois
$569K 50,964 -13,599 -21%
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