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Spero Therapeutics

78 hedge funds and large institutions have $186M invested in Spero Therapeutics in 2020 Q3 according to their latest regulatory filings, with 13 funds opening new positions, 30 increasing their positions, 22 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

36% more repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 22

17% more capital invested

Capital invested by funds: $159M → $186M (+$26.3M)

7.49% more ownership

Funds ownership: 57.17%64.67% (+7.5%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

3% less funds holding

Funds holding: 8078 (-2)

13% less first-time investments, than exits

New positions opened: 13 | Existing positions closed: 15

65% less call options, than puts

Call options by funds: $217K | Put options by funds: $614K

Holders
78
Holders Change
-2
Holders Change %
-2.5%
% of All Funds
1.57%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
13
Increased
30
Reduced
22
Closed
15
Calls
$217K
Puts
$614K
Net Calls
-$397K
Net Calls Change
-$416K
Name Holding Trade Value Shares
Change
Change in
Stake
ACM
1
Aquilo Capital Management
California
$50.2M +$30.2M +2,554,061 +131%
AVAI
2
Atlas Venture Associates IX
Massachusetts
$15.4M
BI
3
BVF Inc
California
$15M +$10.1M +857,794 +176%
RSCM
4
Rock Springs Capital Management
Maryland
$13.8M +$7.35M +621,079 +101%
AI
5
Alphabet Inc
California
$12.4M
BlackRock
6
BlackRock
New York
$12M +$1.5M +126,906 +13%
NHAS
7
Novo Holdings A/S
Denmark
$10.4M
Vanguard Group
8
Vanguard Group
Pennsylvania
$10.4M +$2.29M +193,664 +26%
AG
9
Artal Group
Luxembourg
$6.7M +$650K +54,960 +10%
AIC
10
AWM Investment Company
New York
$5.57M +$3.02M +255,000 +105%
GIM
11
Granahan Investment Management
Massachusetts
$4.17M +$2.45M +207,472 +125%
State Street
12
State Street
Massachusetts
$3.19M -$35.3K -2,982 -1%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$2.58M +$199K +16,854 +8%
Northern Trust
14
Northern Trust
Illinois
$2.36M +$13.7K +1,160 +0.6%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$2.23M +$32.3K +2,729 +1%
SB
16
Samsara BioCapital
California
$1.79M +$1.89M +160,000 New
Renaissance Technologies
17
Renaissance Technologies
New York
$1.71M -$2.09M -176,700 -54%
Jacobs Levy Equity Management
18
Jacobs Levy Equity Management
New Jersey
$1.38M -$741K -62,662 -34%
Russell Investments Group
19
Russell Investments Group
United Kingdom
$1.29M +$274K +23,200 +25%
Alyeska Investment Group
20
Alyeska Investment Group
Illinois
$1.12M +$1.18M +100,000 New
DCM
21
DAFNA Capital Management
California
$1.12M +$1.18M +100,000 New
JP Morgan Chase
22
JP Morgan Chase
New York
$895K -$117K -9,887 -10%
Susquehanna International Group
23
Susquehanna International Group
Pennsylvania
$641K +$203K +17,158 +43%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$575K +$18.8K +1,589 +3%
N
25
Nuveen
North Carolina
$569K -$161K -13,599 -21%

SPRO Hedge Fund Activity: Q3 2020 in Review

78 of the 4,956 institutional investors tracked by Wall St. Rank reported a position in Spero Therapeutics (SPRO) for Q3 2020, worth a combined $186M — up 17% from $159M a quarter earlier.

Sellers outnumbered buyers: 15 funds closed out of SPRO and 13 opened new positions — a net loss of 2 holders — while 22 trimmed existing stakes and 30 added.

The largest buyer was Aquilo Capital Management, adding an estimated $30.2M. The largest seller was Renaissance Technologies, cutting an estimated $2.09M.

  • 78 institutional investors held Spero Therapeutics (SPRO) as of Q3 2020, down from 80 in Q2 2020.
  • Funds reported $186M of Spero Therapeutics stock for Q3 2020, up 17% quarter-over-quarter.
  • 13 funds opened new Spero Therapeutics positions in Q3 2020 and 15 closed out, a net change of -2 holders.
  • The largest Spero Therapeutics buyer in Q3 2020 was Aquilo Capital Management, an estimated $30.2M added.
  • The largest Spero Therapeutics seller in Q3 2020 was Renaissance Technologies, an estimated $2.09M sold.

Based on aggregated 13F filings for Q3 2020.