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Spero Therapeutics
SPRO

Overview Fund Activity

100 hedge funds and large institutions have $180M invested in Spero Therapeutics in 2022 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 15 increasing their positions, 23 reducing their positions, and 8 closing their positions.

Holders
100
Holders Change
+16
Holders Change %
+19.05%
% of All Funds
1.58%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
25
Increased
15
Reduced
23
Closed
8
Calls
$219K
Puts
$15K
Net Calls
+$204K
Net Calls Change
-$181K

Top Buyers

1
ACM
1
Aquilo Capital Management
California
$45.9M
2
Ameriprise
2
Ameriprise
Minnesota
$5.1M
3
Renaissance Technologies
3
Renaissance Technologies
New York
$949K
4
Two Sigma Investments
4
Two Sigma Investments
New York
$686K
5
KCM
5
Knoll Capital Management
Florida
$609K

Top Sellers

1
State Street
1
State Street
Massachusetts
$4.33M
2
GIM
2
Granahan Investment Management
Massachusetts
$986K
3
Rafferty Asset Management
3
Rafferty Asset Management
New York
$0
4
IA
4
IndexIQ Advisors
New York
$0
5
WJWM
5
Williams Jones Wealth Management
New York
$226K
Name Market Value Shares Shares
Change 		Shares
Change %
Two Sigma Advisers
51
Two Sigma Advisers
New York
$143K 16,400 +16,400 New
Jane Street
52
Jane Street
New York
$136K 15,622 +15,622 New
Wells Fargo
53
Wells Fargo
California
$124K 14,283 -8,411 -37%
CSS
54
Cubist Systematic Strategies
Connecticut
$123K 14,144 +14,144 New
Deutsche Bank
55
Deutsche Bank
Germany
$121K 13,885 -1,658 -11%
XT
56
XTX Topco
Cayman Islands
$115K 13,260 +13,260 New
AllianceBernstein
57
AllianceBernstein
Tennessee
$113K 12,934 – –
TRCT
58
Tower Research Capital (TRC)
New York
$108K 12,423 +3,655 +42%
AIG
59
American International Group
New York
$105K 12,015 -845 -7%
Manulife (Manufacturers Life Insurance)
60
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$101K 11,620 -2,436 -17%
HF
61
HRT Financial
New York
$98K 11,277 +11,277 New
State Board of Administration of Florida Retirement System
62
State Board of Administration of Florida Retirement System
Florida
$96K 11,007 – –
EGM
63
Engineers Gate Manager
New York
$95K 10,957 +10,957 New
Citadel Advisors
64
Citadel Advisors
Florida
$94K 10,797 +10,797 New
California State Teachers Retirement System (CalSTRS)
65
California State Teachers Retirement System (CalSTRS)
California
$89K 10,256 -2,482 -19%
RCM
66
Radnor Capital Management
Pennsylvania
$87K 10,000 – –
Bank of America
67
Bank of America
North Carolina
$85K 9,810 -31,843 -76%
Allspring Global Investments
68
Allspring Global Investments
North Carolina
$78K 9,048 -1,138 -11%
Russell Investments Group
69
Russell Investments Group
United Kingdom
$63K 7,250 – –
Simplex Trading
70
Simplex Trading
Illinois
$55K 6,346 +6,346 New
Barclays
71
Barclays
United Kingdom
$35K 3,930 -25,441 -87%
AF
72
Amalgamated Financial
New York
$34K 3,887 +3,887 New
AB
73
Amalgamated Bank
New York
$34K 3,887 +3,887 New
BFC
74
Bedel Financial Consulting
Indiana
$33K 3,837 – –
Legal & General Group
75
Legal & General Group
United Kingdom
$22K 2,581 +114 +5%
1 2
3
4 5