Two Sigma Advisers
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Two Sigma Advisers’s Spero Therapeutics SPRO Stock Holding History

Two Sigma Advisers’s Portfolio SPRO Stock Details SPRO Fund Activity
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Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
2025
Q4 		$505K Buy
2022
Q3 		– Sell
2022
Q2 		$131K Buy
2022
Q1 		$143K Buy
2021
Q2 		– Sell
2021
Q1 		$361K Buy
2020
Q4 		$375K Sell
2020
Q3 		$239K Buy
2020
Q2 		$221K Buy