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Spero Therapeutics
SPRO

Overview Fund Activity

79 hedge funds and large institutions have $15.5M invested in Spero Therapeutics in 2022 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 20 increasing their positions, 22 reducing their positions, and 35 closing their positions.

Holders
79
Holders Change
-21
Holders Change %
-21%
% of All Funds
1.34%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
16
Increased
20
Reduced
22
Closed
35
Calls
$36K
Puts
$34K
Net Calls
+$2K
Net Calls Change
-$202K

Top Buyers

1
BI
1
BVF Inc
California
$2.29M
2
Renaissance Technologies
2
Renaissance Technologies
New York
$696K
3
D.E. Shaw & Co
3
D.E. Shaw & Co
New York
$481K
4
Two Sigma Investments
4
Two Sigma Investments
New York
$324K
5
OMC
5
Oasis Management Company
Cayman Islands
$213K

Top Sellers

1
Ameriprise
1
Ameriprise
Minnesota
$0
2
AIC
2
AWM Investment Company
New York
$0
3
Royal Bank of Canada
3
Royal Bank of Canada
Ontario, Canada
$0
4
GIM
4
Granahan Investment Management
Massachusetts
$0
5
BlackRock
5
BlackRock
New York
$513K
Name Market Value Shares Shares
Change 		Shares
Change %
DTL
51
Dynamic Technology Lab
Singapore
$8K 10,664 +10,664 New
PCM
52
Prelude Capital Management
New York
$8K 10,726 +10,726 New
Simplex Trading
53
Simplex Trading
Illinois
$6K 9,300 +2,954 +47%
Russell Investments Group
54
Russell Investments Group
United Kingdom
$4K 6,400 -850 -12%
Fidelity Investments
55
Fidelity Investments
Massachusetts
$3K 4,120 +4,017 +3,900%
Osaic Holdings
56
Osaic Holdings
Arizona
$2K 2,795 +1,700 +155%
Federated Hermes
57
Federated Hermes
Pennsylvania
$2K 2,579 +2,579 New
JPMorgan Chase & Co
58
JPMorgan Chase & Co
New York
$1K 1,275 -79,897 -98%
Wells Fargo
59
Wells Fargo
California
$1K 891 -13,392 -94%
Legal & General Group
60
Legal & General Group
United Kingdom
$1K 1,934 -647 -25%
UBS Group
61
UBS Group
Switzerland
$1K 755 – –
BCV
62
Banque Cantonale Vaudoise
Switzerland
$1K 2,000 – –
Zurich Cantonal Bank
63
Zurich Cantonal Bank
Switzerland
$1K 1,950 – –
CFB
64
Cullen/Frost Bankers
Texas
$1K 2,000 +1,000 +100%
TWC
65
TD Waterhouse Canada
Ontario, Canada
$410 500 – –
PP
66
PFS Partners
New Jersey
$186 250 – –
Ameriprise
67
Ameriprise
Minnesota
– – -586,642 Closed
AIC
68
AWM Investment Company
New York
– – -372,755 Closed
Royal Bank of Canada
69
Royal Bank of Canada
Ontario, Canada
– – -196,097 Closed
GIM
70
Granahan Investment Management
Massachusetts
– – -113,322 Closed
Charles Schwab
71
Charles Schwab
California
– – -65,547 Closed
Nuveen Asset Management
72
Nuveen Asset Management
Illinois
– – -60,598 Closed
EP
73
Eversept Partners
New York
– – -59,639 Closed
Walleye Capital
74
Walleye Capital
New York
– – -40,009 Closed
State of Wisconsin Investment Board
75
State of Wisconsin Investment Board
Wisconsin
– – -31,600 Closed
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3
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