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Spero Therapeutics

47 hedge funds and large institutions have $21.3M invested in Spero Therapeutics in 2025 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 12 increasing their positions, 6 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more ownership

Funds ownership:

34% less capital invested

Capital invested by funds: $32.1M → $21.3M (-$10.9M)

45% less call options, than puts

Call options by funds: $195K | Put options by funds: $355K

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
47
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$195K
Puts
$355K
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
26
$61.2K
27
$56.4K
28
$56.4K
29
$54.9K
30
$53.7K
31
$51K
32
$41.5K
33
$31.7K
34
$29.7K
35
$18.8K
36
$14K
37
$9K
38
$1.38K
39
$1.03K
40
$545
41
$444
42
$376
43
$376
44
$284
45
$188
46
$75
47
$19
48
49
50