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Spero Therapeutics

50 hedge funds and large institutions have $16.1M invested in Spero Therapeutics in 2024 Q4 according to their latest regulatory filings, with 12 funds opening new positions, 13 increasing their positions, 9 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more first-time investments, than exits

New positions opened: 12 | Existing positions closed: 8

44% more repeat investments, than reductions

Existing positions increased: 13 | Existing positions reduced: 9

9% more funds holding

Funds holding: 4650 (+4)

5.92% more ownership

Funds ownership: 22.84%28.76% (+5.9%)

2% less capital invested

Capital invested by funds: $16.5M → $16.1M (-$391K)

Holders
50
Holders Change
+4
Holders Change %
+8.7%
% of All Funds
0.66%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
12
Increased
13
Reduced
9
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Susquehanna International Group
26
Susquehanna International Group
Pennsylvania
$30.6K -$17.2K -14,464 -33%
DIM
27
DLK Investment Management
California
$29.8K -$2.85K -2,400 -8%
Charles Schwab
28
Charles Schwab
California
$29.4K
PI
29
PFG Investments
New York
$25.3K +$12.6K +10,555 +76%
HF
30
HRT Financial
New York
$15K +$17.5K +14,692 New
Dimensional Fund Advisors
31
Dimensional Fund Advisors
Texas
$10.3K
National Bank of Canada
32
National Bank of Canada
Quebec, Canada
$10.3K
TYCC
33
Texas Yale Capital Corp
Florida
$10.3K +$11.9K +10,000 New
Morgan Stanley
34
Morgan Stanley
New York
$7.18K
Bank of America
35
Bank of America
North Carolina
$5.71K -$127 -107 -2%
US Bancorp
36
US Bancorp
Minnesota
$5.31K +$5.95K +5,000 +3,311%
Simplex Trading
37
Simplex Trading
Illinois
$5K +$4.98K +4,189 +455%
Fidelity Investments
38
Fidelity Investments
Massachusetts
$4.42K +$1.37K +1,150 +37%
WWP
39
WR Wealth Planners
Missouri
$2.68K
CFB
40
Cullen/Frost Bankers
Texas
$2.06K
TRCT
41
Tower Research Capital (TRC)
New York
$957 +$785 +660 +245%
Osaic Holdings
42
Osaic Holdings
Arizona
$304
SS
43
SBI Securities
Japan
$219 +$253 +213 New
Wells Fargo
44
Wells Fargo
California
$206
RMP
45
Richards, Merrill & Peterson
Washington
$155 +$178 +150 New
UBS Group
46
UBS Group
Switzerland
$145 -$20.7K -17,388 -99%
NA
47
NewEdge Advisors
Louisiana
$103
CA
48
CoreCap Advisors
Michigan
$52 -$169 -142 -74%
FDCDDQ
49
Federation des caisses Desjardins du Quebec
Quebec, Canada
$31
BNP Paribas Financial Markets
50
BNP Paribas Financial Markets
France
$12

SPRO Hedge Fund Activity: Q4 2024 in Review

50 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Spero Therapeutics (SPRO) for Q4 2024, worth a combined $16.1M — down 2.4% from $16.5M a quarter earlier.

Buyers outnumbered sellers: 12 funds opened new SPRO positions and 8 closed out — a net gain of 4 holders — while 13 added to existing stakes and 9 trimmed.

The largest buyer was Murchinson, opening a new position worth an estimated $1.04M. The largest seller was Novo Holdings A/S, exiting entirely with an estimated $628K sold.

  • 50 institutional investors held Spero Therapeutics (SPRO) as of Q4 2024, up from 46 in Q3 2024.
  • Funds reported $16.1M of Spero Therapeutics stock for Q4 2024, down 2.4% quarter-over-quarter.
  • 12 funds opened new Spero Therapeutics positions in Q4 2024 and 8 closed out, a net change of +4 holders.
  • The largest Spero Therapeutics buyer in Q4 2024 was Murchinson, an estimated $1.04M added.
  • The largest Spero Therapeutics seller in Q4 2024 was Novo Holdings A/S, an estimated $628K sold.

Based on aggregated 13F filings for Q4 2024.