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Spero Therapeutics
SPRO

Overview Fund Activity

100 hedge funds and large institutions have $180M invested in Spero Therapeutics in 2022 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 15 increasing their positions, 23 reducing their positions, and 8 closing their positions.

Holders
100
Holders Change
+16
Holders Change %
+19.05%
% of All Funds
1.58%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
25
Increased
15
Reduced
23
Closed
8
Calls
$219K
Puts
$15K
Net Calls
+$204K
Net Calls Change
-$181K

Top Buyers

1
ACM
1
Aquilo Capital Management
California
$45.9M
2
Ameriprise
2
Ameriprise
Minnesota
$5.1M
3
Renaissance Technologies
3
Renaissance Technologies
New York
$949K
4
Two Sigma Investments
4
Two Sigma Investments
New York
$686K
5
KCM
5
Knoll Capital Management
Florida
$609K

Top Sellers

1
State Street
1
State Street
Massachusetts
$4.33M
2
GIM
2
Granahan Investment Management
Massachusetts
$986K
3
Rafferty Asset Management
3
Rafferty Asset Management
New York
$0
4
IA
4
IndexIQ Advisors
New York
$0
5
WJWM
5
Williams Jones Wealth Management
New York
$226K
Name Market Value Shares Shares
Change 		Shares
Change %
Bank of New York Mellon
26
Bank of New York Mellon
New York
$636K 73,070 -1,930 -3%
Morgan Stanley
27
Morgan Stanley
New York
$635K 72,996 +22,511 +45%
KCM
28
Knoll Capital Management
Florida
$609K 70,000 +70,000 New
Susquehanna International Group
29
Susquehanna International Group
Pennsylvania
$584K 67,084 -8,099 -11%
Charles Schwab
30
Charles Schwab
California
$571K 65,547 – –
BCM
31
Bourgeon Capital Management
Connecticut
$549K 63,096 +11,850 +23%
Millennium Management
32
Millennium Management
New York
$533K 61,261 +61,261 New
EP
33
Eversept Partners
New York
$519K 59,639 +59,639 New
Nuveen Asset Management
34
Nuveen Asset Management
Illinois
$516K 60,598 – –
PPA
35
Parametric Portfolio Associates
Washington
$384K 44,168 +44,168 New
DADC
36
D.A. Davidson & Co
Montana
$381K 43,800 – –
SPA
37
Sentinel Pension Advisors
Massachusetts
$365K 42,000 +11,800 +39%
Walleye Capital
38
Walleye Capital
New York
$348K 40,009 +40,009 New
Stifel Financial
39
Stifel Financial
Missouri
$328K 37,728 +7,842 +26%
State of Wisconsin Investment Board
40
State of Wisconsin Investment Board
Wisconsin
$275K 31,600 – –
Marshall Wace
41
Marshall Wace
United Kingdom
$227K 26,027 +26,027 New
WJWM
42
Williams Jones Wealth Management
New York
$226K 26,000 -49,000 -65%
GCP
43
GSA Capital Partners
United Kingdom
$225K 25,916 +25,916 New
Janney Montgomery Scott
44
Janney Montgomery Scott
Pennsylvania
$222K 25,500 – –
RhumbLine Advisers
45
RhumbLine Advisers
Massachusetts
$215K 24,740 +5,479 +28%
TI
46
Trexquant Investment
Connecticut
$210K 24,151 +24,151 New
Assenagon Asset Management
47
Assenagon Asset Management
Luxembourg
$201K 23,123 +23,123 New
D.E. Shaw & Co
48
D.E. Shaw & Co
New York
$162K 18,646 +18,646 New
GG
49
Gofen & Glossberg
Illinois
$152K 17,500 – –
New York State Common Retirement Fund
50
New York State Common Retirement Fund
New York
$149K 17,123 -36,605 -68%
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