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Spero Therapeutics
SPRO

100 hedge funds and large institutions have $180M invested in Spero Therapeutics in 2022 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 15 increasing their positions, 23 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,360% more call options, than puts

Call options by funds: $219K | Put options by funds: $15K

213% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 8

19% more funds holding

Funds holding: 84 → 100 (+16)

1.4% more ownership

Funds ownership: 61.24% → 62.63% (+1.4%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

35% less repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 23

43% less capital invested

Capital invested by funds: $316M → $180M (-$137M)

Holders
100
Holders Change
+16
Holders Change %
+19.05%
% of All Funds
1.58%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
25
Increased
15
Reduced
23
Closed
8
Calls
$219K
Puts
$15K
Net Calls
+$204K
Net Calls Change
-$181K

Top Buyers

Rank Fund Capital Flow
1
ACM
Aquilo Capital Management
California
+$3.25M
2
Ameriprise
Ameriprise
Minnesota
+$2.29M
3
Renaissance Technologies
Renaissance Technologies
New York
+$1.12M
4
Two Sigma Investments
Two Sigma Investments
New York
+$808K
5
KCM
Knoll Capital Management
Florida
+$717K

Top Sellers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
-$3.55M
2
GIM
Granahan Investment Management
Massachusetts
-$2.72M
3
Rafferty Asset Management
Rafferty Asset Management
New York
-$560K
4
WJWM
Williams Jones Wealth Management
New York
-$502K
5
IA
IndexIQ Advisors
New York
-$459K
Name Holding Trade Value Shares
Change 		Change in
Stake
Bank of New York Mellon
26
Bank of New York Mellon
New York
$636K -$19.8K -1,930 -3%
Morgan Stanley
27
Morgan Stanley
New York
$635K +$231K +22,511 +45%
KCM
28
Knoll Capital Management
Florida
$609K +$717K +70,000 New
Susquehanna International Group
29
Susquehanna International Group
Pennsylvania
$584K -$83K -8,099 -11%
Charles Schwab
30
Charles Schwab
California
$571K – – –
BCM
31
Bourgeon Capital Management
Connecticut
$549K +$121K +11,850 +23%
Millennium Management
32
Millennium Management
New York
$533K +$628K +61,261 New
EP
33
Eversept Partners
New York
$519K +$611K +59,639 New
N
34
Nuveen
North Carolina
$516K – – –
PPA
35
Parametric Portfolio Associates
Washington
$384K +$453K +44,168 New
DADC
36
D.A. Davidson & Co
Montana
$381K – – –
SPA
37
Sentinel Pension Advisors
Massachusetts
$365K +$121K +11,800 +39%
Walleye Capital
38
Walleye Capital
New York
$348K +$410K +40,009 New
Stifel Financial
39
Stifel Financial
Missouri
$328K +$80.3K +7,842 +26%
State of Wisconsin Investment Board
40
State of Wisconsin Investment Board
Wisconsin
$275K – – –
Marshall Wace
41
Marshall Wace
United Kingdom
$227K +$267K +26,027 New
WJWM
42
Williams Jones Wealth Management
New York
$226K -$502K -49,000 -65%
GCP
43
GSA Capital Partners
United Kingdom
$225K +$266K +25,916 New
Janney Montgomery Scott
44
Janney Montgomery Scott
Pennsylvania
$222K – – –
RhumbLine Advisers
45
RhumbLine Advisers
Massachusetts
$215K +$56.1K +5,479 +28%
TI
46
Trexquant Investment
Connecticut
$210K +$247K +24,151 New
Assenagon Asset Management
47
Assenagon Asset Management
Luxembourg
$201K +$237K +23,123 New
D.E. Shaw & Co
48
D.E. Shaw & Co
New York
$162K +$191K +18,646 New
GG
49
Gofen & Glossberg
Illinois
$152K – – –
New York State Common Retirement Fund
50
New York State Common Retirement Fund
New York
$149K -$375K -36,605 -68%
1
2
3 4 5

SPRO Hedge Fund Activity: Q1 2022 in Review

100 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Spero Therapeutics (SPRO) for Q1 2022, worth a combined $180M — down 43% from $316M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new SPRO positions and 8 closed out — a net gain of 17 holders — while 15 added to existing stakes and 23 trimmed.

The largest buyer was Aquilo Capital Management, adding an estimated $3.25M. The largest seller was State Street, cutting an estimated $3.55M.

  • 100 institutional investors held Spero Therapeutics (SPRO) as of Q1 2022, up from 84 in Q4 2021.
  • Funds reported $180M of Spero Therapeutics stock for Q1 2022, down 43% quarter-over-quarter.
  • 25 funds opened new Spero Therapeutics positions in Q1 2022 and 8 closed out, a net change of +17 holders.
  • The largest Spero Therapeutics buyer in Q1 2022 was Aquilo Capital Management, an estimated $3.25M added.
  • The largest Spero Therapeutics seller in Q1 2022 was State Street, an estimated $3.55M sold.

Based on aggregated 13F filings for Q1 2022.