First Trust Health Care AlphaDEX Fund
238 hedge funds and large institutions have $506M invested in First Trust Health Care AlphaDEX Fund in 2025 Q4 according to their latest regulatory filings, with 38 funds opening new positions, 58 increasing their positions, 81 reducing their positions, and 16 closing their positions.
138% more first-time investments, than exits
New positions opened: 38 | Existing positions closed: 16
21% more call options, than puts
Call options by funds: $580K | Put options by funds: $478K
9% more funds holding
Funds holding: 219 → 238 (+19)
8% more capital invested
Capital invested by funds: $469M → $506M (+$36.7M)
3.06% more ownership
Funds ownership: 50.8% → 53.86% (+3.1%)
28% less repeat investments, than reductions
Existing positions increased: 58 | Existing positions reduced: 81
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Raymond James Financial
St Petersburg,
Florida
|
+$5.37M |
| 2 |
Envestnet Asset Management
Chicago,
Illinois
|
+$3.34M |
| 3 |
Two Sigma Investments
New York
|
+$2.55M |
| 4 |
Cambridge Investment Research Advisors
Fairfield,
Iowa
|
+$2.19M |
| 5 |
AssetMark Inc
Concord,
California
|
+$1.57M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
-$8.96M |
| 2 |
Citadel Advisors
Miami,
Florida
|
-$4.33M |
| 3 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$1.17M |
| 4 |
UBS Group
Zurich,
Switzerland
|
-$927K |
| 5 |
HFP
Holistic Financial Partners
Indianapolis,
Indiana
|
-$891K |
FXH Hedge Fund Activity: Q4 2025 in Review
238 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in First Trust Health Care AlphaDEX Fund (FXH) for Q4 2025, worth a combined $506M — up 7.8% from $469M a quarter earlier.
Buyers outnumbered sellers: 38 funds opened new FXH positions and 16 closed out — a net gain of 22 holders — while 58 added to existing stakes and 81 trimmed.
The largest buyer was Raymond James Financial, adding an estimated $5.37M. The largest seller was Royal Bank of Canada, cutting an estimated $8.96M.
- 238 institutional investors held First Trust Health Care AlphaDEX Fund (FXH) as of Q4 2025, up from 219 in Q3 2025.
- Funds reported $506M of First Trust Health Care AlphaDEX Fund stock for Q4 2025, up 7.8% quarter-over-quarter.
- 38 funds opened new First Trust Health Care AlphaDEX Fund positions in Q4 2025 and 16 closed out, a net change of +22 holders.
- The largest First Trust Health Care AlphaDEX Fund buyer in Q4 2025 was Raymond James Financial, an estimated $5.37M added.
- The largest First Trust Health Care AlphaDEX Fund seller in Q4 2025 was Royal Bank of Canada, an estimated $8.96M sold.
Based on aggregated 13F filings for Q4 2025.