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Spero Therapeutics
SPRO

Overview Fund Activity

39 hedge funds and large institutions have $10.9M invested in Spero Therapeutics in 2025 Q1 according to their latest regulatory filings, with 2 funds opening new positions, 9 increasing their positions, 10 reducing their positions, and 12 closing their positions.

Holders
39
Holders Change
-11
Holders Change %
-22%
% of All Funds
0.53%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
2
Increased
9
Reduced
10
Closed
12
Calls
$7K
Puts
$2K
Net Calls
+$5K
Net Calls Change
+$5K

Top Buyers

1
Geode Capital Management
1
Geode Capital Management
Massachusetts
$378K
2
Squarepoint
2
Squarepoint
New York
$66.9K
3
Mackenzie Financial
3
Mackenzie Financial
Ontario, Canada
$151K
4
EWA
4
EP Wealth Advisors
California
$11.9K
5
Northern Trust
5
Northern Trust
Illinois
$72.7K

Top Sellers

1
Acadian Asset Management
1
Acadian Asset Management
Massachusetts
$626K
2
Renaissance Technologies
2
Renaissance Technologies
New York
$699K
3
Citadel Advisors
3
Citadel Advisors
Florida
$44.1K
4
Jane Street
4
Jane Street
New York
$0
5
VF
5
Virtu Financial
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
FDCDDQ
51
Federation des caisses Desjardins du Quebec
Quebec, Canada
– – -30 Closed
CFGS
52
Concourse Financial Group Securities
Alabama
– – – –
1 2
3