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Septerna Inc

82 hedge funds and large institutions have $838M invested in Septerna Inc in 2025 Q3 according to their latest regulatory filings, with 10 funds opening new positions, 31 increasing their positions, 17 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

more funds holding in top 10

Funds holding in top 10:

8% less funds holding

Funds holding: 8982 (-7)

38% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 16

88% less call options, than puts

Call options by funds: $1.7M | Put options by funds: $14M

Holders
82
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$1.7M
Puts
$14M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
26
$3.15M
27
$1.74M
28
$1.66M
29
$1.57M
30
$1.51M
31
$1.11M
32
$1.07M
33
$1.02M
34
$971K
35
$969K
36
$673K
37
$658K
38
$566K
39
$519K
40
$516K
41
$476K
42
$451K
43
$416K
44
$389K
45
$379K
46
$379K
47
$343K
48
$266K
49
$257K
50
$242K