RhumbLine Advisers
SEPN

RhumbLine Advisers’s Septerna Inc SEPN Stock Holding History

RhumbLine Advisers’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$926K Buy
27,636
+1,032
+4% +$29.3K ﹤0.01% 2359
2026
Q1 		$639K Buy
26,604
+185
+0.7% +$4.86K ﹤0.01% 2450
2025
Q4 		$737K Sell
26,419
-1,185
-4% -$28.3K ﹤0.01% 2403
2025
Q3 		$519K Sell
27,604
-968
-3% -$12.7K ﹤0.01% 2671
2025
Q2 		$302K Buy
28,572
+5,254
+23% +$43.3K ﹤0.01% 2986
2025
Q1 		$135K Buy
23,318
+3,323
+17% +$37.9K ﹤0.01% 3288
2024
Q4 		$458K Buy
+19,995
New +$473K ﹤0.01% 2725

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

RhumbLine Advisers's SEPN Position: Q2 2026 in Review

RhumbLine Advisers increased its Septerna Inc (SEPN) stake by 3.9% in Q2 2026, buying an estimated $29.3K and bringing the position to 27,636 shares worth $926K. The position accounts for ﹤0.01% of the portfolio, ranked #2359.

RhumbLine Advisers first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • RhumbLine Advisers held 27,636 shares of Septerna Inc worth $926K as of Q2 2026.
  • RhumbLine Advisers bought 1,032 Septerna Inc shares in Q2 2026, an estimated $29.3K.
  • Septerna Inc made up ﹤0.01% of RhumbLine Advisers's portfolio in Q2 2026, its #2359 holding.
  • RhumbLine Advisers first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on RhumbLine Advisers's 13F filing for Q2 2026, filed 12 Aug 2026.