SEPN

Septerna, Inc. Common Stock

71 hedge funds and large institutions have $262M invested in Septerna, Inc. Common Stock in 2025 Q1 according to their latest regulatory filings, with 20 funds opening new positions, 25 increasing their positions, 12 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
71
Holders Change
Holders Change %
0%
% of All Funds
0.96%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
20
Increased
25
Reduced
12
Closed
19
Calls
$157K
Puts
$444K
Net Calls
-$287K
Net Calls Change
-$287K
Name Holding Trade Value Shares
Change
Shares
Change %
RCM
1
RA Capital Management
Massachusetts
$40.5M
TGV
2
TRV GP V
Massachusetts
$36M
BI
3
BVF Inc
California
$25.5M +$11.3M +1,944,100 +79%
TGV
4
TRV GP VI
Massachusetts
$24.4M +$6.13M +1,059,203 +34%
SB
5
Samsara BioCapital
California
$18.2M +$2.2M +380,608 +14%
DCM
6
Driehaus Capital Management
Illinois
$18.1M +$3.09M +533,055 +21%
SL
7
Siren LLC
Connecticut
$12.8M
DTC
8
Deep Track Capital
Connecticut
$11.1M
Goldman Sachs
9
Goldman Sachs
New York
$8.39M -$1.3M -224,958 -13%
ACA
10
Avoro Capital Advisors
New York
$7.74M +$1.32M +227,500 +20%
BlackRock
11
BlackRock
New York
$7.29M -$2.42M -418,822 -25%
CCM
12
Catalio Capital Management
New York
$5.93M
Vanguard Group
13
Vanguard Group
Pennsylvania
$5.76M +$58K +10,012 +1%
CC
14
Checkpoint Capital
California
$4.78M +$4.78M +824,878 New
SCM
15
Sio Capital Management
New York
$4.57M +$2.99M +516,983 +190%
SCM
16
Soleus Capital Management
Connecticut
$4.35M +$440K +75,944 +11%
ACM
17
ADAR1 Capital Management
Texas
$4.17M +$4.17M +720,848 New
WP
18
Woodline Partners
California
$3.37M +$1.64M +282,585 +94%
CC
19
Casdin Capital
New York
$3.2M
Millennium Management
20
Millennium Management
New York
$2.53M +$2.53M +436,564 New
Geode Capital Management
21
Geode Capital Management
Massachusetts
$2.37M +$168K +29,063 +8%
State Street
22
State Street
Massachusetts
$2M +$416K +71,828 +26%
UBS Group
23
UBS Group
Switzerland
$1.39M +$761K +131,477 +121%
Northern Trust
24
Northern Trust
Illinois
$915K +$59.4K +10,264 +7%
LGM
25
Logos Global Management
California
$777K